Mechanisms of Pteridine-Ommochrome Interactions in Drosophila Melanogaster

Ommochromes (brown pigments) and certain pteridines (red pigments), contribute to the typical reddish-brown eye color of wild-type Drosophila melanogaster. Each pigment is the end product of a seemingly unrelated metabolic pathway (Ziegler 1961; Kaufman 1967a). Mutations which alter the synthesis of these pigments are manifested as numerous variations in eye color (Lindsley and Grell 1967). Suppressed production of brown pigment results in the accumulation of ommochrome precursors which in some instances alters the production of drosopterins and their intermediates. "Pteridine mutants" accumulate pteridine intermediates and show altered ommochrome formation (Hadorn and Mitchell 1951) . Therefore, an interaction between the two biosynthetic pathways is indicated.

Grantor dc:publisher

Creighton University

Year dc:date.issued

1974

Author dc:creator

• Cirone Jr., Joseph B.

Advisor dc:contributor.advisor

• Nickla, Harry

• Drosophila Melanogaster

Statement dc:rights

• A non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above.

Language dc:language.iso

en_US

Handle dc:identifier.uri

http://hdl.handle.net/10504/114404

OAI identifier oai:identifier

oai:cdr.creighton.edu:10504/114404