Antibiotic Effects of Dimethyl Sulfoxide and Synthetic Polyphenols on E. Coli Cells

<p>There is increasing interest in polyphenols due to their potential medicinal and antibiotic applications. Naturally occurring polyphenols, such as curcumin, have garnered tremendous attention. However, synthetic polyphenols commonly used in biochemistry experiments have not been sufficiently explored. The purpose of this study is to determine the effect of dimethyl sulfoxide on the cellular uptake of synthetic polyphenols. Three synthetic polyphenols (Phenol Red, Congo Red, and Bromophenol Blue) were tested for their antibiotic properties and compared to the antibiotic activity of curcumin. Our results show that phenol red does not interact with the bacterial membrane even in the presence of 30% DMSO, while Bromophenol Blue and Congo Red exhibit weak inhibition of bacterial growth.</p>

Name thesis:degree_name

Chemistry

Level thesis:degree_level

Thesis

Discipline thesis:degree_discipline

Chemistry

Year dc:date.available

2018

Author dc:creator

• Cardenas, Camila

Contributors dc:contributor

• Dr. Jonathan Meyers
• Dr. Kerri Taylor
• Dr. Cindy Ticknor

• Antibiotic Effects
• Dimethyl
• Sulfoxide
• Synthetic Polyphenols
• E. Coli
• Biochemistry
• Chemistry

Language dc:language

English

Repository record dc:identifier

https://csuepress.columbusstate.edu/theses_dissertations/337

OAI identifier oai:identifier

oai:csuepress.columbusstate.edu:theses_dissertations-1341