There is increasing interest in polyphenols due to their potential medicinal and antibiotic applications. Naturally occurring polyphenols, such as curcumin, have garnered tremendous attention. However, synthetic polyphenols commonly used in biochemistry experiments have not been sufficiently explored. The purpose of this study is to determine the effect of dimethyl sulfoxide on the cellular uptake of synthetic polyphenols. Three synthetic polyphenols (Phenol Red, Congo Red, and Bromophenol Blue) were tested for their antibiotic properties and compared to the antibiotic activity of curcumin. Our results show that phenol red does not interact with the bacterial membrane even in the presence of 30% DMSO, while Bromophenol Blue and Congo Red exhibit weak inhibition of bacterial growth.
","abstract_html":"<p>There is increasing interest in polyphenols due to their potential medicinal and antibiotic applications. Naturally occurring polyphenols, such as curcumin, have garnered tremendous attention. However, synthetic polyphenols commonly used in biochemistry experiments have not been sufficiently explored. The purpose of this study is to determine the effect of dimethyl sulfoxide on the cellular uptake of synthetic polyphenols. Three synthetic polyphenols (Phenol Red, Congo Red, and Bromophenol Blue) were tested for their antibiotic properties and compared to the antibiotic activity of curcumin. Our results show that phenol red does not interact with the bacterial membrane even in the presence of 30% DMSO, while Bromophenol Blue and Congo Red exhibit weak inhibition of bacterial growth.</p>","abstract_has_math":false,"creators":["Cardenas, Camila"],"institution":null,"degree_name":"Chemistry","degree_level":"Thesis","degree_discipline":"Chemistry","degree_department":null,"school":null,"contributors":["Dr. Jonathan Meyers","Dr. Kerri Taylor","Dr. Cindy Ticknor"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2018,"date_issued":"2018-01-01T08:00:00Z","date_published":"2018-01-01T08:00:00Z","updated_at":"2026-07-24T01:45:01Z","subjects":["Antibiotic Effects","Dimethyl","Sulfoxide","Synthetic Polyphenols","E. Coli","Biochemistry","Chemistry"],"languages":["English"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://csuepress.columbusstate.edu/theses_dissertations/337","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Dr. Jonathan Meyers","Dr. Kerri Taylor","Dr. Cindy Ticknor"]},{"key":"dc:creator","label":"Author","values":["Cardenas, Camila"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.available","label":"Dc Date Available","values":["2020-01-23T08:00:00Z"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Chemistry"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Chemistry"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Antibiotic Effects","Dimethyl","Sulfoxide","Synthetic Polyphenols","E. Coli","Biochemistry","Chemistry"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["English"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://csuepress.columbusstate.edu/theses_dissertations/337"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["There is increasing interest in polyphenols due to their potential medicinal and antibiotic applications. Naturally occurring polyphenols, such as curcumin, have garnered tremendous attention. However, synthetic polyphenols commonly used in biochemistry experiments have not been sufficiently explored. The purpose of this study is to determine the effect of dimethyl sulfoxide on the cellular uptake of synthetic polyphenols. Three synthetic polyphenols (Phenol Red, Congo Red, and Bromophenol Blue) were tested for their antibiotic properties and compared to the antibiotic activity of curcumin. Our results show that phenol red does not interact with the bacterial membrane even in the presence of 30% DMSO, while Bromophenol Blue and Congo Red exhibit weak inhibition of bacterial growth.
"]},{"key":"dc:title","label":"Title","values":["Antibiotic Effects of Dimethyl Sulfoxide and Synthetic Polyphenols on E. Coli Cells"]}]}],"canonical_facts":{"dc:contributor":["Dr. Jonathan Meyers","Dr. Kerri Taylor","Dr. Cindy Ticknor"],"dc:creator":["Cardenas, Camila"],"dc:date.available":["2020-01-23T08:00:00Z"],"dc:description.abstract":["There is increasing interest in polyphenols due to their potential medicinal and antibiotic applications. Naturally occurring polyphenols, such as curcumin, have garnered tremendous attention. However, synthetic polyphenols commonly used in biochemistry experiments have not been sufficiently explored. The purpose of this study is to determine the effect of dimethyl sulfoxide on the cellular uptake of synthetic polyphenols. Three synthetic polyphenols (Phenol Red, Congo Red, and Bromophenol Blue) were tested for their antibiotic properties and compared to the antibiotic activity of curcumin. Our results show that phenol red does not interact with the bacterial membrane even in the presence of 30% DMSO, while Bromophenol Blue and Congo Red exhibit weak inhibition of bacterial growth.
"],"dc:identifier":["https://csuepress.columbusstate.edu/theses_dissertations/337"],"dc:language":["English"],"dc:subject":["Antibiotic Effects","Dimethyl","Sulfoxide","Synthetic Polyphenols","E. Coli","Biochemistry","Chemistry"],"dc:title":["Antibiotic Effects of Dimethyl Sulfoxide and Synthetic Polyphenols on E. Coli Cells"],"thesis:degree_discipline":["Chemistry"],"thesis:degree_level":["Thesis"],"thesis:degree_name":["Chemistry"]},"updated_at":"2026-07-24T01:45:01Z"}