The crystal structure of a mutant nitrile hydratase

Nitrile hydratases can be used as industrial biocatalysts. They catalyze the conversion of nitriles to their corresponding amides. These industrial biocatalysts have recently gained attention due to the economic production of industrial commodities such as acrylamide and nicotinamide (Thomas et at., 2002). Nitrile hydratases (NHases) are metalloenzymes made up of α and β subunits, and exist mostly as heterotetramers (αβ)₂. They are categorized into Co-containing and Fe-containing types depending on their co-factor requirements.

Grantor dc:publisher.institution

Department of Molecular and Cell Biology

Year dc:date.issued

2006

Author dc:creator

• Kwofie, Samuel Kojo

Advisor dc:contributor.advisor

• Cowan, DA

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/4284

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/4284