The role of signal transducer and activator of transcription-3 (STAT-3) in ischaemic and pharmacological preconditioning

Ischemic preconditioning is a protective mechanism whereby repetitive transient ischaemia confer protection against the subsequent prolonged lethal ischaemia that is observed during myocardial infarction. This protective phenomenon that lessens myocardial infarction can be mimicked by the cytokine tumor necrosis factor alpha (TNFα) but the signalling pathways involved still remain unclear.

Grantor dc:publisher.institution

Department of Medicine

Year dc:date.issued

2006

Author dc:creator

• Suleman, Naushaad

Advisors dc:contributor.advisor

• Lecour, S
• Smith, R

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/3473

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/3473