Exercise induced neuroprotection in spontaneuosly running rats

We investigated the effects of voluntary exercise on neuroprotection after unilateral lesions with 6-hydroxydopamine. Rats were divided into runners (had access to running wheel) and non-runners (their running wheels were immobilised). Two weeks after injection of the neurotoxin, the rats were injected with apomorphine and the number of ipsilateral and contralateral rotations was counted with contralateral rotations of greater than 150 considered to represent striatal dopamine neuron destruction of 70% or above.

Grantor dc:publisher.institution

Department of Human Biology

Year dc:date.issued

2007

Author dc:creator

• Mabandla, Musa Vuyisile

Advisors dc:contributor.advisor

• Gibson, Alan St Clair
• Russell, Vivienue A

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/3263

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/3263