A study comparing the effects of vincristine with those of ionizing radiation on the root meristem of Vicia faba

Vincristine and vinblastine, two closely related alkaloids are extracted from the Madagaskar Periwinkle, Vinca rosea Linn. They have been shown to be effective oncolytic agents and cause arrest of mitosis at the metaphase stage, similar to that of colchicine andcolcimid. Clinically, vincristine has been found to produce a complete remission in patients with acute leukaemia. Tumour regression in patients with Hodgkin's disease, lymphosarcoma and certain childhood solid tumours have also been reported.

Grantor

Department of Human Biology

Year dc:date.issued

1972

Author dc:creator

• Haddad, Dawne Merle

• Meristem
• Radiation effects

Handle dc:identifier.uri

https://hdl.handle.net/11427/31950

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/31950