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Division of Medical Biochemistry
Functional consequences of South African mutations of the HIV-1 co-receptor, CCR5
Abstract
dc:description.abstractFour mutations of the CCR5 receptor have been identified in the South African population, but the effects of these mutations on CCR5 function and HIV infection are unknown. We have used in vitro methods to assess the ffect of the mutations, Asp2Val, Leu107Phe, Arg225Gln and Arg225stop, on CCR5 interactions with chemokine ligands and HIV.
Degree
thesis:*- Grantor dc:publisher.institution
- Division of Medical Biochemistry
- Year dc:date.issued
- 2007
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Folefoc, Asongna Theresia Forkem
- Advisors dc:contributor.advisor
-
- Flanagan, Colleen
- Katz, Arieh
Rights
- Language dc:language.iso
- eng
Identifiers
dc:identifier.*- Handle dc:identifier.uri
- http://hdl.handle.net/11427/3128
- OAI identifier oai:identifier
- oai:open.uct.ac.za:11427/3128