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Department of Medicine
The role of IL-4 and Th2-like cytokines in pulmonary tuberculosis
Abstract
dc:description.abstractTuberculosis (TB) vaccine candidates have been mostly ineffective and it remains unclear as to what constitutes protective host immunity. Despite high levels of IFN-γ at the site of disease, the Th1 cytokine associated with protection, many individuals still have progressive active TB. Whether a Th2-like immune response (IL-4; IL-4δ2; IL-9) can subvert protective host immunity requires clarification.
Degree
thesis:*- Grantor dc:publisher.institution
- Department of Medicine
- Year dc:date.issued
- 2015
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Pooran, Anil
- Advisors dc:contributor.advisor
-
- Dheda, Keertan
- Blackburn, Jonathan
Rights
- Language dc:language.iso
- eng
Identifiers
dc:identifier.*- Handle dc:identifier.uri
- http://hdl.handle.net/11427/16784
- OAI identifier oai:identifier
- oai:open.uct.ac.za:11427/16784