Conformational studies of some small biological molecules and their interactions with metal ions

The solid Cu(II) and Co(II) complexes and complex salts of some thiamine analogues have been prepared. Their electronic spectra, I.R. spectra and Magnetic Moments are presented and discussed in terms of suggested coordination geometries for the complexes. In addition the solution conformations of the Gd(III), Dy(III) and Ho (III) complexes of some 3' , 5' cyclic nucleotides were determined quantitatively using NMR line broadening and line shifting techniques. Reactions of Mn(II) with the cyclic nucleotides were used to find the preferred binding sites on the ligands also using line broadening techniques.

Grantor dc:publisher.institution

Department of Chemistry

Year dc:date.issued

1976

Author dc:creator

• Russell, Jill Catherine

Advisor dc:contributor.advisor

• Fazakerley, G V

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/16771

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/16771