{"id":{"repo_id":"cape-town","oai_identifier":"oai:open.uct.ac.za:11427/16771"},"canonical_url":"https://search.dev.ndltd.org/etd/cape-town/oai:open.uct.ac.za:11427/16771","repository":{"repo_id":"cape-town","name":"University of Cape Town","base_url":"https://open.uct.ac.za/oai/request"},"display":{"title":"Conformational studies of some small biological molecules and their interactions with metal ions","abstract":"The solid Cu(II) and Co(II) complexes and complex salts of some thiamine analogues have been prepared. Their electronic spectra, I.R. spectra and Magnetic Moments are presented and discussed in terms of suggested coordination geometries for the complexes. In addition the solution conformations of the Gd(III), Dy(III) and Ho (III) complexes of some 3' , 5' cyclic nucleotides were determined quantitatively using NMR line broadening and line shifting techniques. Reactions of Mn(II) with the cyclic nucleotides were used to find the preferred binding sites on the ligands also using line broadening techniques.","abstract_html":"The solid Cu(II) and Co(II) complexes and complex salts of some thiamine analogues have been prepared. Their electronic spectra, I.R. spectra and Magnetic Moments are presented and discussed in terms of suggested coordination geometries for the complexes. In addition the solution conformations of the Gd(III), Dy(III) and Ho (III) complexes of some 3' , 5' cyclic nucleotides were determined quantitatively using NMR line broadening and line shifting techniques. Reactions of Mn(II) with the cyclic nucleotides were used to find the preferred binding sites on the ligands also using line broadening techniques.","abstract_has_math":false,"creators":["Russell, Jill Catherine"],"institution":"Department of Chemistry","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Fazakerley, G V"],"committee_chairs":[],"committee_members":[],"year":1976,"date_issued":"1976","date_published":"1976","updated_at":"2026-07-22T22:23:34Z","subjects":[],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/11427/16771","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Fazakerley, G V"]},{"key":"dc:creator","label":"Author","values":["Russell, Jill Catherine"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2016-02-05T07:12:25Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2016-02-05T07:12:25Z"]},{"key":"dc:date.issued","label":"Date","values":["1976"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Department of Chemistry"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Cape Town"]},{"key":"dc:type","label":"Dc Type","values":["Doctoral Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["Doctoral"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["PhD"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/11427/16771"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["The solid Cu(II) and Co(II) complexes and complex salts of some thiamine analogues have been prepared. Their electronic spectra, I.R. spectra and Magnetic Moments are presented and discussed in terms of suggested coordination geometries for the complexes. In addition the solution conformations of the Gd(III), Dy(III) and Ho (III) complexes of some 3' , 5' cyclic nucleotides were determined quantitatively using NMR line broadening and line shifting techniques. Reactions of Mn(II) with the cyclic nucleotides were used to find the preferred binding sites on the ligands also using line broadening techniques."]},{"key":"dc:title","label":"Title","values":["Conformational studies of some small biological molecules and their interactions with metal ions"]}]}],"canonical_facts":{"dc:contributor.advisor":["Fazakerley, G V"],"dc:creator":["Russell, Jill Catherine"],"dc:date.accessioned":["2016-02-05T07:12:25Z"],"dc:date.available":["2016-02-05T07:12:25Z"],"dc:date.issued":["1976"],"dc:description.abstract":["The solid Cu(II) and Co(II) complexes and complex salts of some thiamine analogues have been prepared. Their electronic spectra, I.R. spectra and Magnetic Moments are presented and discussed in terms of suggested coordination geometries for the complexes. In addition the solution conformations of the Gd(III), Dy(III) and Ho (III) complexes of some 3' , 5' cyclic nucleotides were determined quantitatively using NMR line broadening and line shifting techniques. Reactions of Mn(II) with the cyclic nucleotides were used to find the preferred binding sites on the ligands also using line broadening techniques."],"dc:identifier.uri":["http://hdl.handle.net/11427/16771"],"dc:language.iso":["eng"],"dc:publisher.department":["Department of Chemistry"],"dc:publisher.institution":["University of Cape Town"],"dc:title":["Conformational studies of some small biological molecules and their interactions with metal ions"],"dc:type":["Doctoral Thesis"],"dc:type.qualificationlevel":["Doctoral"],"dc:type.qualificationname":["PhD"]},"updated_at":"2026-07-22T22:23:34Z"}