The role of interleukin-4 receptor alpha on smooth muscle cells during helminth infection

Interleukin-4 receptor alpha (IL-4Ra) signaling, mediated by the ligands IL-4 and IL- 13, is important for effective host protection during murine Nippostrongylus brasiliensis (N. brasiliensis) and Schistosoma mansoni (S. manson!) infection. Among other cell types, IL-4Ra responsive smooth muscle cells influence immunological responses and are needed for host protection during N. brasiliensis and S. mansoni infection.

Grantor dc:publisher.institution

Division of Immunology

Year dc:date.issued

2011

Author dc:creator

• Brombacher, Tiroyaone M H

Advisor dc:contributor.advisor

• Brombacher, Frank

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/12245

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/12245