The protective effects of the antioxidant combination of ferulic acid with vitamins C and E against UV-induced photodamage in human skin cells

This study assessed the ability of 0.8 mM ferulic acid (FA), in combination with vitamins C and E, to reduce the effect of UVA-induced photodamage in human epidermal (HaCaTs) and dermal skin cells (primary human fibroblasts (HFbs) and murine 3T3 cells). Pretreatment with the FA and vitamins C and E (vEC) combination solution reduced UVAinduced ROS in human fibroblasts while pre-treatment with vEC individually led to a reduction in HaCaTs.

Grantor dc:publisher.institution

Department of Medicine

Year dc:date.issued

2010

Author dc:creator

• Bone, Emma Lewis

Advisor dc:contributor.advisor

• Davids, Lester

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/12167

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/12167