Immunological characterization of the HIV-tuberculosis associated immune reconstitution inflammatory syndrome

While the integration of anti-TB and cART therapies is associated with substantial clinical improvement in the majority of patients, HIV-Tuberculosis associated Immune Reconstitution Inflammatory Syndrome (TB-IRIS) has been shown to occur in a significant subset of these patients. TB-IRIS is an inflammatory complication of the combined treatments for HIV-1 and tuberculosis, which is being reported increasingly, particularly in areas endemic to both diseases. This work aimed to characterise the immunopathogenesis of paradoxical HIV-Tuberculosis associated immune reconstitution inflammatory syndrome.

Grantor dc:publisher.institution

Institute of Infectious Disease and Molecular Medicine

Year dc:date.issued

2011

Author dc:creator

• Tadokera, Rabecca

Advisors dc:contributor.advisor

• Wilkinson, Robert J
• Wilkinson, Katalin

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/11589

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/11589