Immunological analysis of pericardial tuberculosis

Pericardial tuberculosis (TB) offers a relevant human model to study TB at the site of disease and to determine the effect of HIV-1 infection. 96 Patients with pericardial TB were recruited into this study, 68 of whom were HIV-1 infected. Where clinically indicated, pericardiocentesis was performed to drain pericardial fluid and blood was drawn. The data derived from the study provide novel insight into the immune response in the pericardium to TB infection. Furthermore, HIV-1 infection caused a dysregulation of the immune response.

Grantor dc:publisher.institution

Division of Immunology

Year dc:date.issued

2011

Author dc:creator

• Matthews, Kerryn

Advisors dc:contributor.advisor

• Wilkinson, Katalin
• Wilkinson, Robert J
• Mayosi, Bongani

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/11101

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/11101