Computational rationale for the selective inhibition of the herpes simplex virus type 1 uracil-DNA glycosylase enzyme

Hendricks, Umraan

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Department of Chemistry

Computational rationale for the selective inhibition of the herpes simplex virus type 1 uracil-DNA glycosylase enzyme

dc:creator Hendricks, Umraan

dc:date.issued2011

Abstract

dc:description.abstract

In this thesis I will investigate the binding pocket and analyse the nature of binding of the 6-(4-Alkylanilino)-uracil inhibitors in hsvUDG and hUDG to provide a platform for the development of improved inhibitors.

Degree

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Grantor dc:publisher.institution: Department of Chemistry
Year dc:date.issued: 2011

Author and committee

dc:creator, dc:contributor.*

Author dc:creator: Hendricks, Umraan
Advisor dc:contributor.advisor: Naidoo, Kevin J

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Language dc:language.iso: eng

Identifiers

dc:identifier.*

Handle dc:identifier.uri: http://hdl.handle.net/11427/11049
OAI identifier oai:identifier: oai:open.uct.ac.za:11427/11049

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Harvested from: University of Cape Town
Base URL: open.uct.ac.za/oai/request
Last updated: 2026-07-22
Source record: OAI-PMH GetRecord

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citation

Hendricks, Umraan. Computational rationale for the selective inhibition of the herpes simplex virus type 1 uracil-DNA glycosylase enzyme. Department of Chemistry, 2011. http://hdl.handle.net/11427/11049

Computational rationale for the selective inhibition of the herpes simplex virus type 1 uracil-DNA glycosylase enzyme

Abstract

Degree

Author and committee

Rights

Identifiers

Chain of custody

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