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Division of Virology
Evaluation of a reverse tetracycline inducible system in recombinant BCG to improve stability and immunogenicity
Abstract
dc:description.abstractThe aim of this study is to utilise the tetracycline dependent gene regulation system to down-regulate recombinant antigen expression in BCG during the expansion of seed stocks and up-regulate expression prior to or post vaccination.
Degree
thesis:*- Grantor dc:publisher.institution
- Division of Virology
- Year dc:date.issued
- 2011
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Mbele, Prisca
- Advisors dc:contributor.advisor
-
- Chapman, Ros
- Williamson, Anna-Lise
Rights
- Language dc:language.iso
- eng
Identifiers
dc:identifier.*- Handle dc:identifier.uri
- http://hdl.handle.net/11427/10930
- OAI identifier oai:identifier
- oai:open.uct.ac.za:11427/10930