Expanding the utility of human induced pluripotent stem cell (hiPSC) forward programmed megakaryocytes: Creating a disease model of Thrombocytopenia with Absent Radii (TAR) syndrome and developmental stage appropriate cells

[Restricted]

Name dc:type.qualificationname

Doctor of Philosophy (PhD)

Level dc:type.qualificationlevel

Doctoral

Grantor dc:publisher.institution

University of Cambridge

Year dc:date.issued

2022

Author dc:creator

• Warland, James

Advisor dc:contributor.advisor

• Ghevaert, Cedric

• CRISPR
• forward programming
• LYL1
• megakaryocyte
• platelet
• pluripotent stem cell
• RBM8A
• RUNX3
• thrombocytopenia absent radii (TAR) syndrome
• transcription factor

Licence

• https://www.repository.cam.ac.uk/bitstreams/1fc0a512-83c4-4715-9213-2564cc120ad3/download
• https://www.rioxx.net/licenses/all-rights-reserved/

Language dc:language

eng

Author Identifier

0000-0003-1060-1865

OAI identifier oai:identifier

oai:www.repository.cam.ac.uk:1810/358102