Metabolism of testosterone by tissue enzymes

From a series of in vitro incubations with human skin the existence of an enzyme system which metabolizes testosterone to [triangle]^4-androstene-3, 17-dione and "polar compounds" has been established. Several enzyme systems are felt to be active in testosterone breakdown by human skin; some of these from "polar compounds", one of them forms [triangle]^4-androstene-3,17-dione, while others form additional unknown ketonic compounds. These skin enzymes were found to vary quantitatively among different subjects. [TRUNCATED]

Grantor dc:publisher

Boston University

Year dc:date.issued

1957

Author dc:creator

• Simpson, Norma J.

Statement dc:rights

• Based on investigation of the BU Libraries' staff, this work is free of known copyright restrictions.

Language dc:language.iso

en_US

Dc Identifier Other

b14753273

OAI identifier oai:identifier

oai:open.bu.edu:2144/24589