Substrate metabolism and acid secretion in the rat stomach

The aim of this work was, firstly, to identify which substrates could support acid secretion by rat parietal cells and secondly, to investigate the intracellular events involved in stimulus transduction in rat parietal cells. A technique was developed which enabled satisfactory measurements of arteriovenous differences across the rat stomach in vivo. Glucose, D-3-hydroxybutyrate and branched-chain amino acids were taken up by the stomach wall under control and acid-secreting (pentagastrin-stimulated) conditions. The pattern of substrate metabolism appeared unaffected by stimulation of acid secretion...

Name dc:type.qualificationname

Ph.D.

Level dc:type.qualificationlevel

doctoral

Grantor dc:publisher.institution

Aston University

Year dc:date.issued

1984

Author dc:creator

• Anderson, Neil Grant

DOI dc:identifier.doi

https://doi.org/10.48780/publications.aston.ac.uk.00010547

OAI identifier oai:identifier

oai:publications.aston.ac.uk:10547