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Ajou University

Association of Lamivudine-Resistant Mutational Patterns with the Antiviral Effect of Adefovir in Patients with Chronic Hepatitis B

Abstract

dc:description

"ABSTRACT ⅰ TABLE OF CONTENTS ⅱ LIST OF TABLES iii ABBREVIATION iv I. INTRODUCTION 1 II. MATERIALS AND METHODS 3 A. Patients 3 B. Blood tests 3 C. Detection of mutations by restriction fragment mass polymorphism (RFMP) Analysis 5 D. Sequencing analysis 6 E. Definition 6 F. Statistical analysis 7 III.RESULTS 8 A. Virologic and biochemical response to adefovir 8 B. Antiviral efficacy of Adefovir between the HBeAg-positive and -negative Groups 8 C. Baseline hepatitis B virus polymerase mutations 8 D. Effect of lamivudine-resistant mutational pattern on the virologic and biochemical response to adefovir 12 IV. DISCUSSION 15 V. CONCLUSION 18 REFERENCES 19 국문요약 24 "

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • 차, 충근
Contributors dc:contributor
  • 조, 성원
  • 대학원 의학과
  • 199924555

Rights

Language dc:language
en

Identifiers

dc:identifier.*
OAI identifier oai:identifier
oai:repository.ajou.ac.kr:201003/1306

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Ajou University
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Last updated
2026-07-24
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citation

차, 충근. Association of Lamivudine-Resistant Mutational Patterns with the Antiviral Effect of Adefovir in Patients with Chronic Hepatitis B. 2011. http://repository.ajou.ac.kr/handle/201003/1306