Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 29 for “"vector competence"”.
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The role of midgut serine proteases in Aedes aegypti vector competence
… arboviruses infecting the invertebrate host (vector) through the alimentary tract may exploit serine proteases in the midgut to enhance vector infection. Recent genetic and biochemical experiments have demonstrated that dengue virus type 2 (DENV-2) may require proteolytic processing by midgut …
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The evolution and genetics of vector competence in mosquito disease vectors
Vector competence is a complex characteristic which governs an insect's ability to acquire, support the development and transmit a parasite from one host to another. It influences variation in disease transmission among mosquito populations, hence affecting disease epidemiology. In this project, I …
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Vector Competence of Aedes aegypti for Zika Virus and Effects of Colonization
The following dissertation aims to determine how vector colonization of influences the vector competence of Aedes aegypti for Zika virus (ZIKV) as well as the microbiome as a correlating factor. Ae. aegypti is the vector of multiple arthropod-borne viruses including dengue, yellow fever, and Zika …
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BIOLOGY AND VECTOR COMPETENCE OF THE ANOPHELINE MOSQUITOES OF MYANMAR WITH SPECIAL CONSIDERATION OF ANOPHELES DIRUS
… seasonal prevalence, adult behaviour and their vector competence. Some general aspects of anopheline behaviour are discussed. Classification has been made of all recorded species in relation to malaria transmission and the distribution of malaria in Myanmar as follows: dissection records, …
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Impact of Mosquito Age and Insecticide Exposure on Vector Competence of Aedes albopictus (Diptera: Culicidae) for Zika Virus
… sexually and congenitally (from human to human). Vector-virus interactions influencing vector competence (the ability for a mosquito to become infected with and transmit a pathogen) vary and depend on biological (e.g., mosquito age) and environmental factors (e.g., temperature). A mosquito's …
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The vector competence and vectorial capacity of Aedes albopictus for ross river virus as a function of temperature
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2025-10-20 without embargo terms
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Vector competence of Ochlerotatus trivittatus (Coquillett), Aedes albopictus (Skuse), and Culex pipiens (L) (Diptera: Culicidae) for West Nile virus
… species of mosquitoes are the primary amplifying vectors. Many species of mammals are also susceptible to WNV but develop viremias that seldom exceed 105.0 CID50s/ml. Mammals may play a significant role in WNV ecology if mosquitoes that feed on them during periods of viremia can be infected and …
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Factors influencing arbovirus transmission: vector competence and the effects of virus infection on repellent response, oxidative stress, and glutathione-S-transferase activity
… and Cache Valley (CVV) viruses are mosquito-vectored diseases that cause significant morbidity and mortality in humans and animals. Transmission of these viruses are dependent on numerous factors including vector competence and the effects of mosquito-virus interactions. We conducted vector …
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Studies of Susceptibility of Broad-Headed Skinks (<em>Eumeces laticeps</em>) and Laboratory Mice (<em>Mus musculus</em>) to Strain MI-2 of <em>Borrelia burgdorferi</em> and Vector Competence of the Tick <em>Ixodes scapularis</em>
<p>Reservoir competence of the broad-headed skink, <em>Eameces laticeps</em>, for <em>Borrelia burgdorferi</em> was evaluated. Attempts to infect broad-headed skinks with MI-2 strain spirochetes were unsuccessful. Spirochetes could not be isolated from various tissues of seven lizards at least 30 …
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Identification and Characterization of a Relish-type NF-kB, DvRelish in Dermacentor variabilis, the American Dog Tick
Ticks are important worldwide as vectors of bacteria, viruses, and parasites. Pathogenic and non-pathogenic Spotted fever group (SFG) Rickettsia are maintained and transmitted by ticks with specific hard tick-Rickettsia pairings evident in nature. The pathogenic SFG Rickettsia rickettsii is …
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The tick response to Rickettsial dissemination during typical and atypical Rickettsial infection
Ticks are the only disease vectors for spotted fever group (SFG) Rickettsia which are obligate intracellular bacteria belonging to the genus Rickettsia. In nature, ticks maintain the infection of SFG Rickettsia via vertical and horizontal transmission. However, the prevalence of rickettsial …
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Bloodmeal determinants of Zika virus infection of Aedes (Stegomyia) aegypti mosquitoes
… I first determined the general basal levels of vector competence these species demonstrated for various strains of ZIKV. Subsequently experiments directly comparing artificial bloodmeals derived from murine and non-human primates to ZIKV viremic animals were conducted to ascertain what, if any, …
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Secondary Transmission Dynamics of the West Nile Virus in Mosquitoes
… 2013 season individuals across 9 different WNV vector species were collected throughout the Niagara region with 1023 tested for the presence of naturally occurring WNV TOT. None of the samples showed signs of TOT. A single gravid female Culex pipiens tested positive for WNV, but no viral RNA was …
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Forest disturbance, mosquito vector ecology and La Crosse virus dynamics in southwestern Virginia
… the temperate forest mosquito community, LACV vectors, and the LACV amplifying vertebrate host (chipmunks) were impacted by logging. This research was conducted across an experimental FCD gradient (from least to most disturbed: contiguous control, fragmented control, clearcut, and high-leave …
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Genetic factors affecting the RNA interference pathway of Aedes aegypti mosquitoes
Aedes aegypti mosquitoes are the vectors of many significant arboviruses that cause tremendous social and economic impact. RNA interference (RNAi) plays a crucial role in the vector competence of mosquitoes and is often targeted in studies involving mosquito innate immunity, genetics-based vector …
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Comparative Transmission and Pathogenesis of La Crosse Virus (LACV) Lineages and Evidence for LACV Circulation in Virginia Wildlife
… and host animal populations, or (4) reduced vector competence in local mosquito populations. In chapter three, we explore the vector competence of Aedes albopictus and Aedes triseriatus from the range of lineage III (Connecticut) and from the historic LACV range (Virginia) to transmit LACV …
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Characterizing ERAD and Antioxidant Response in Ixodes scapularis ISE6 Cells during Borrelia Infection
… </em>and BB<em> </em>infection within the tick vector<em> </em>that contribute to understanding its molecular mechanism of survival within the tick before transmission to the mammalian host. The goal of this research is to elucidate the molecular determinants of vector competence to prevent …
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Characterization of rickettsial infection dynamics within Dermacentor variabilis and Amblyomma maculatum
… associated with their reservoir host and vector, the tick. Rickettsial colonization and maintenance within the arthropod is a key component of vector competence and pathogen transmission to the mammalian host. Contemporary detection of novel tick hosts for rickettsial species, combined …
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Linking mosquito midgut and virus population biology at the molecular and cellular level
Vector competence (VC) refers to the efficiency of pathogen transmission by vectors. Each step in infection of a mosquito vector constitutes a barrier to transmission that may impose bottlenecks on virus populations. West Nile virus (WNV) is maintained by multiple mosquito species with varying VC. …
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Discovery and characterization of a newly emerged DENV serotype.
… a transmission cycle in nature. Furthermore, the vector competence of Aedes aegypti and Aedes albopictus mosquitoes, the two main vectors of human-endemic DENV, was evaluated. The potential of these vectors to be infected and transmit the novel virus was demonstrated. Initial structural studies …
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