Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 74 for “"vascular system"”.
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The effects of metformin on the vascular system
Macrovascular contraction and relaxation effects of metformin were measured using a Mulvany Halpern myograph. Mouse aortic ring sections were treated for 1 and 4 hours in vitro with metformin at 10-5M, and for 2, 4 and 8 weeks in vivo with metformin at 250mg/kg/day. The rings were contacted with …
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Origins and Development of the Embryonic Vascular System in Xenopus
Each step of vascular development needs to be carefully regulated; endothelial precursors must be specified, these cells then proliferate and coalesce to form vascular cords, and finally they lumenate, undergo angiogenic branching and remodeling, and recruit smooth muscle cells to establish a …
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Histology and histochemistry of atherosclerotic lesions in the pit fowl hen vascular system
Iliac complexes from pit fowl hens, in 3 groups of 8 animals each having mean ages of 1.0, 2.5, and 4.4 years, were examined histologically and histochemically for spontaneous atherosclerotic plaques. The purpose being (1) clarification of the role of specific arterial components in elaboration of …
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Comparative histology and histochemistry of the vascular system in the White Plymouth Rock hen and the pit fowl hen
The abdominal aorta, brachial and iliac arteries, of 8 White Plymouth Rock hens and 8 pit fowl hens were examined histochemically. The purpose being to (1) determine whether arterial anatomical differences exist; (2) compare the vessels of both groups histochemically; (3) uncover differences in …
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Mechanical characterization and self-healing in synthetic vascularized materials
… throughout the material volume using a microvascular network of microchannels that serve as conduits of flow and permit fluid transport throughout the material volume, in much the same way that vascular systems transport nutrients and biochemical components throughout living organisms. …
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Aspectos anatômicos de órgãos vegetativos (folha e caule) de Dioclea grandiflora, e sua importância química e farmacológica.
… dorsiventral; Board revoluto; main rib and the vascular system biconvexos, with a sheath of sclerenchymatous cells surrounding vas cular cylinder; angular tissue. Peciólulo displays the contour semicircula. The vascular system is formed by a single side beam wrapped in circle, involving the …
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The use of small molecules to illuminate vascular development
Development of the vascular system is a multifactorial process. Its proper establishment has a big impact on life. Not only is this process essential for organismal growth but abnormal blood vessel formation leads to several pathologies. In some cases the disease itself triggers changes to the …
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3D cyclic olefin copolymer (COC) microfluidic chip fabrication using hot embossing method for cell culture platform
A microfluidic system has been developed for studying the factors inducing different responses of cells in vascular system using a three-dimensional microenvironment. The devices have been transferred from PDMS to a platform in cyclic olefin copolymer (COC) which has advantages in terms of …
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Distribution and function of TRP ion channels in primary sensory neurons
… neurons in culture and nerve fibres in the vascular system. These findings highlight TRPA1 as a novel ion channel in the vascular system and provide novel pharmacological tools for investigating the role of this ion channel. Whether activation of TRPA1 in the vascular system explains the …
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Nanoparticle toxicity and molecular mechanisms in fish: A case study with silver nanoparticles
… effects and mechanisms of metal-based NPs on the vascular system. <em>In vitro</em> studies have shown that NPs are anti-angiogenic because they cause inflammation, oxidative stress, and apoptosis of endothelial cells resulting in increased permeability and decreased proliferation and migration. …
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THE VASCULAR RESPONSE WITHIN THE ISLET DURING BETA CELL DEVELOPMENT AND REGENERATION
… this mechanism and the potential role of the vascular system, neonatal rats were injected with streptozotocin to exacerbate this normal loss of β cells. Immunohistochemical and quantitative RNA analysis was performed to observe the ontogeny of changes to microvasculature, endocrine tissue, and …
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Evaluation of the microcirculation of the equine small intestine following intramural distention and reperfusion
… decompression (60 minutes) on the intramural vascular patterns of the equine small intestine was evaluated in 7 anesthetized horses. The vascular system of experimental and control segments were injected with a blue-colored radiopaque medium for microangiography and histology or a diluted …
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Design and use of an environmental control platform for studying vascular cell function in three-dimensional scaffolds
… and smooth muscle cells are the core of the vascular system. Vessels are created and repaired through the processes of angiogenesis and arteriogenesis. Endothelial cells are the initial cells that migrate and proliferate during the process, followed by smooth muscle cell movement and …
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Segmentation et extraction de caractéristiques des vaisseaux sanguins cérébraux à l'aide de l'IRM
The neurovascular coupling is a growing field; it studies the effects of cerebral activity on the behaviour of cerebral blood flow (CBF) and the blood vessels themselves. With the help of magnetic resonance imaging (MRI), it is possible to obtain images such as susceptibility weighted imaging (SWI) …
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Extracellular Matrix Contributions to Early Vascular Development and Pericyte Precursor Dynamics
The vasculature is a highly intricate system of "highways" that shuttles blood from the heart to every tissue and organ in the human body. These vessels are responsible for carrying oxygen, trafficking hormones, delivering nutrients, and removing waste products from the body. The formation of a …
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Danio rerio (Hamilton, 1822) širdies ir kraujagyslių sistemos vystymosi ir regeneracinių mechanizmų tyrimai /
… (Hamilton, 1822) is a powerful vertebrate model system, which provides a unique combination of advantages that are important for an investigation of cardiovascular development and regeneration. However, conditional mutagenesis, which is essential for dissecting a role of developmental genes in …
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Studying the mechanisms of cardiovascular development and regeneration in Danio rerio (Hamilton, 1822) /
… (Hamilton, 1822) is a powerful vertebrate model system, which provides a unique combination of advantages that are important for an investigation of cardiovascular development and regeneration. However, conditional mutagenesis, which is essential for dissecting a role of developmental genes in …
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OVEREXPRESSION OR REDUCED BIOAVAILABILITY OF VEGF DURING MOUSE POST-NATAL INTESTINAL DEVELOPMENT ALTERS THE PROLIFERATION OF INTESTINAL STEM CELL PROGENITOR CELLS
<p>Vascular Endothelial Growth Factor (VEGF) is a highly conserved ligand that is involved in the regulation of angiogenesis and vasculogenesis, however, alternative roles of the ligand have been emerging. Organisms such as jellyfish and <em>Drosophila</em> contain VEGF homologs, yet they do not …
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Evolution and ecology of guineafowl
… possible anatomical adaptations in the vascular system of the head and neck of Numida meleagris, 7. determine the likely mechanism of population limitation in N. meleagris. This dissertation consists of seven published or submitted papers which relate to one or more of the aims listed …
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Nuclear magnetic resonance microscopy and diffusion
… probe. It is one of the most stable microimaging system designed and fully equipped for microscopic fMRI study. This work is an advancement of using MRI to study fundamental neuron science and cell signal pathways in vivo. NMR Microscopy of pancreatic islet of NOD-SCID mice in vitro has shown the …
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