Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 454 for “"titration"”.
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Computer simulation of titration behavior in proteins
… the continuum electrostatics-based multiple site titration theory based on solvent accessibility is proposed, and it is shown that this model results in improved agreement of calculated pK$\rm\sb{a}$ values with experiment when a low protein interior dielectric constant is used. The techniques …
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Registered Nurse Diabetes Medication Titration at Clinic X
… their perceptions of diabetes medication titration as well as what training and/or support they feel they will need. The author encourages the usage of the survey results in designing the training program.</p>
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Molecular titration by MicroRNAs and target mimic inhibitors
… a mathematical model describing molecular titration of target mRNAs by miRNAs. The model predicted, and experiments confirmed, that the ultrasensitive regime could be shifted to higher target mRNA levels by increasing the miRNA concentration or the number of miRNA binding sites in the 3' …
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Isothermal Titration Calorimetry Uncovers Substrate Promiscuity of Bicupin Oxalate Oxidase
… often confound data interpretation. Isothermal titration calorimetry (ITC) measures heat changes that occur during a reaction. Therefore, ITC can measure reaction rates where both the substrates and products are spectrophotometrically silent and when the reaction products are unknown. In this …
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Parameters of nicotine titration in addicted and non-addicted cigarette smokers
Nicotine titration was studied in cigarette smokers not interested in cutting down or quitting smoking. Forty smokers were classified as high nicotine dependent (n=20) and low nicotine dependent (n=20) using a validated tolerance questionnaire. Subjects were randomized into baseline (n=10) or …
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Structure-based theoretical characterisation of the redox-dependent titration behaviour of cytochrome bc1
… of its catalytic mechanism. The analysis of the titration behaviour of cytochrome bc1 is however complicated by its membrane environment, its high number of titratable sites, their interaction with each other and with redox-active groups, and the conformational variability of the CoQ oxidation …
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An isoperibol calorimeter for the investigation of biochemical kinetics and isothermal titration calorimetry
Isothermal titration calorimetry is a technique used to measure the enthalpy change associated with a molecular binding interaction. From these data, the binding constant for the reaction can be determined. In the scope of a larger project to design a high sensitivity instrument for collecting such …
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The titration of an immunogenic agent against Leptospira pomona using Syrian golden hamsters (Cricetus auratus)
Tests on hamsters reveal that there is a decided protective index from the soluble antigen prepared by the acid-heat extraction of living cultures of Leptospira pomona. They also reveal that the antigen must be given in quantities sufficiently small to be amenable to the system of the test animal …
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A Study of the Potentiometric Curve Obtained by the Titration of Ferrous Ions with Potassium Dichromate
… method for the determination of iron by titration with potassium dichromate. The author in his own words tells why he developed this method and preferred it to other well- known analytical methods.
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Solving the crystallographic structure of the Cl2J construct and occupancy titration trials to quantitatively determine isomer ratio
… bonding energies in opposition. Occupancy titrations were conducted to quantify isomeric ratios of halogen bond versus hydrogen bond stabilized junctions (X- and H-isomers, respectively) within these crystals. The initial estimate of the isomer ratios of the Cl2J construct was 50/50 …
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Determining the solubility of haematin and haem-drug complexes at relevant pH in aqueous medium via spectrophotometric titration
… a previous study, UV– visible spectrophotometric titration experiments of haematin with sodium hydroxide were performed. The optimal incubation time periods allowing for complete sample equilibration were determined to be 16 days at both 10°C and 20°C, 12 days at 25°C and 8 days at both 37°C and …
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Determining the digestible lysine requirement of 22 to 47 week-old Lohmann laying hens using two requirement titration methodologies
… of modern day laying hens using two different titration methods. One thousand six hundred and eighty Lohmann LS Lite caged hens were allotted to 15 dietary treatments using increasing crude protein (CP) or constant CP DLYS titration methodologies from 22 to 47 weeks of age. From Week 0 to 11 …
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A Study of the Accuracy of Colorimetric Determinations of Ascorbic Acid with that of Titration with 2 ,6 - Dichlorophenol-Indolphenol
… of determining the vitamin C content is that of titration by means of the dye 2,6-dichlorophenol-indolphenol, originally suggested by Tillmans, as is described in The Chemistry and Physiology of the Vitamins by H. R. Rosenberg.
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Inverse Monte Carlo simulation of biomolecular conformation and coarse-grained molecular modeling of chondroitin sulfate conformation, titration, and osmotic pressure
The first part of this thesis is concerned with the solution structure determination problem. Whereas many biomacromolecules, such as proteins, can be adequately characterized by a single conformation in solution, numerous other important molecules (e.g., nucleic acids, carbohydrates, and …
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Isothermal Titration Calorimetry Studies Of Protein-Mediated Interactions And Preliminary Structural Studies Of Tandem Pdz1-2 Domain Of Psd-95 Protein
… 2.0 and 3.0 uM) were obtained from calorimetric titrations. The weak interaction is consistent with the hypothesis of frataxin acting as an iron chaperone. Frataxin must be able to form a favorable interface with its protein partners and also easily release the metal. Although this thermodynamic …
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