Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 22 for “"tissue phantom"”.
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Average Dielectric Property Analysis of Non-Uniform Structures: Tissue Phantom Development, Ultra-Wideband Transmission Measurements, and Signal Processing Techniques
… with properties representing biological tissues and robust mechanical properties were developed. Reconfigurable tissue phantoms were created from combinations of these materials. In addition to testing the average property algorithms, these phantoms are well suited to testing a variety of …
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Calculation of Neutron Fluence-to-Dose Index Conversion Factors for the Standard Icru Tissue Phantom by the Monte Carlo Method
Made available in DSpace on 2014-12-14T06:26:06Z (GMT). No. of bitstreams: 1 7811221.pdf: 6872930 bytes, checksum: f215c7f7d666eb9881298cc5aefe2a5e (MD5) Previous issue date: 1978
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Characterizing hydrogel imposed strain fields on brain tissue phantom for use in neural implant device coatings in presence of micromotion
Glial scar tissue forms in the brain as a response to the implant injury and hampers the effectiveness of the implant treatment. Constant relative micromotion between the mechanically mismatched neural implant and brain tissue is thought to play a key role glial scar formation. This study …
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Accurate noninvasive monitoring of fetal tissue oxygenation level
… achieves <3% estimation error in a two-layer tissue phantom. Additionally, we perform in-vivo experiments to show that our system is able to detect reduced tissue oxygenation index (TOI) levels in a human arm, through a human tissue phantom, and can perform transabdominal fetal monitoring in …
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A detailed design analysis of a lumenally delivered, flexible, balloon-assisted, sterile endoscopic overtube.
… most accurate material model for human gastric tissue, FEA analysis of the balloon dilation, experimentally validating these results using a silicone tissue phantom, and the paper design of a theoretical prototype. Tensile testing the human gastric tissue provided the only material properties …
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Interferometric Synthetic Aperture Microscopy (ISAM) Reconstruction and Characterization in a High Numerical Aperture System
… includes the image reconstruction of a tissue phantom containing nano-particles both for OCT and ISAM, and system characterization includes quantitative assessment of the confocal parameter, point spread function, and phase stability measurements. Several potential applications also are …
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Design of an endoscopic biopsy needle with flexural members
As a minimally invasive means of extracting a tissue sample from a patient, current endoscopic biopsy needles generally do not preserve tissue histology and often require multiple attempts to obtain a tissue sample. This paper presents an endoscopic biopsy needle with internal flexures that enable …
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A non-clinical method to simultaneously estimate thermal conductivity, volumetric specific heat, and perfusion of in-vivo tissue
… specific heat, and perfusion of in-vivo tissue. The heat transfer through the tissue was modeled using a modified Pennes' equation. Using a least-squares parameter estimation method with regularization, the thermal properties could be estimated from the temperature response to the known …
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Optical Imaging Of Tissue Physiology With Exogenous Contrast Agents
… emitting exogenous contrast agents in living tissue. The first set of experiments concurrently measured cerebral blood flow and bothintravascular- and extravascular-tissue oxygen concentration in a rat brain during functional activation; the new instrumentation needed to collect this …
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DEVELOPMENT OF A GENERAL LETHAL CRITERION FOR IRREVERSIBLE ELECTROPORATION
… minimizing the damage to surrounding healthy tissue. The determination of ablation zone requires a criterion that can judge whether tumor tissue is dead or lethal after IRE ablation. Currently, the cell lethality criterion is represented by the electric field strength, i.e., a threshold called …
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Novel Biophotonic Imaging Techniques for Assessing Women's Reproductive Health
… of concept measurements on a calibration socket, tissue phantom, and in vivo human data. Once the instrument is fully characterized, it is applied in a clinical trial in which in vivo human vaginal gel thickness distributions. The gel distribution data obtained by the modalities are compared in …
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Dual-modality thermoacoustic and photoacoustic imaging
… for safe and efficient thermotherapy. Using a tissue phantom, these noninvasive methods have been demonstrated to have a high temperature sensitivity of 0.15 0C at 2 s temporal resolution: 20 signal averages).
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Three Experiments on Complex Fluids
… cellulose. This material has been used as a tissue phantom in testing the behavior of medical devices in MRI scanners. We find it behaves as a typical entangled polymer, and flows in response to local heating, such as could occur due to eddy-current heating of metallic devices in an MR …
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Optimal Control of Thermal Damage to Biological Materials
… cancer treatment modality that raises cancerous tissue to cytotoxic temperature levels for roughly 30 to 45 minutes. Hyperthermia treatment planning refers to the use of computational models to optimize the heating protocol to be used in a hyperthermia treatment. This thesis presents a method to …
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All-optical photoacoustic and laser-ultrasonic imaging in heterogeneous tissue
… in medicine to non-invasively probe and image tissues up to centimeters deep. Ultrasonic (US) imaging is the most well-known modality used to image acoustic density and velocity contrasts. US is useful for imaging overall structure in tissue, however, acoustic contrasts are relatively low in …
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Assessment of the Measurement Repeatability and Sensitivity of a Noninvasive Blood Perfusion Measuring Probe
… is the local, non-directional blood flow through tissue. It is measured as the volumetric flow rate of blood through a given volume of tissue. One method that has been developed for measuring blood perfusion is a probe that measures the temperature response of the tissue when a thermal event is …
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Assessment of the Repeatability and Sensitivity of the Thermoelectric Perfusion Probe
… system that cyclically heats and cools tissue to measure blood perfusion. The probe produces the thermal event with a thermoelectric cooler and then measures the resulting heat flux and temperatures: the arterial temperature and the sensor temperature (the temperature between the heat …
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Design and Validation of Medical Devices for Photothermally Augmented Treatments
… Porous Media Infusion of therapeutic agents into tissue is makes use of two mass transport modes: advective transport, and molecular diffusion. Bulk infusion into a 0.6% wt agarose phantom was modeled as an infinite, homogenous, and isotropic porous medium saturated with the same solvent used in …
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Effective Cancer Therapy Design Through the Integration of Nanotechnology
… is limited due to nonspecific heating of target tissue, leading to healthy tissue injury and extended treatment durations. These therapies can be further compromised due to heat shock protein (HSP) induction in tumor regions where non-lethal temperature elevation occurs, thereby imparting …
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Design and Fabrication of Optomechanical Formalin Fixation Monitoring Systems Integrated with a Millifluidic Device
… project (Chapter 2, 3, and 4) is to develop a tissue quality monitoring system for an automated millifluidic system for pathology and the development cycle includes design, fabrication, testing, and evaluation of the systems. In our lab, a novel automated millifluidic system for cancer …
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