Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 22 for “"tissue interface"”.
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The Design and Implementation of an Extensible Brain-Computer Interface
An implantable brain computer interface: BCI) includes tissue interface hardware, signal conditioning circuitry, analog-to-digital conversion: ADC) circuitry and some sort of computing hardware to discriminate desired waveforms from noise. Within an experimental paradigm the tissue interface and …
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Analysis and Design of Electrodes for Deep Brain Stimulation
… vivo</italic>. Characterization of the electrode-tissue interface impedance is required to quantify the composition of charge transfer to the brain tissue. The composition of charge transfer was dependent on both the current density and the sinusoidal frequency. The assumption of the DBS electrode …
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Nonlinear simulation of tumor growth and chemotherapy
… growth and chemotherapy, where the tumor-healthy tissue interface is a moving deformable boundary. In the process, we improve upon existing techniques and develop new finite difference and ghost fluid / level set methods to attain full second-order accuracy for the first time in the context of …
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Vision Based Surgical Tool Tracking with Robot Kinematics Prior
… feedback is a major drawback --- discerning tool-tissue interactions can be unintuitive and can ultimately result in unintentional tissue damage. Directly sensing forces at the tool-tissue interface is theoretically possible using tool tip mounted force sensors, but this approach is not amenable …
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A system for efficient neural stimulation with energy recovery
An analog VLSI-based low-power neural tissue stimulator is presented as a part of the MIT and Massachusetts Eye and Ear Infirmary Retinal Implant Project to develop a prosthesis for restoring some useful vision to patients blinded by retinal degeneration. Such a prosthesis would receive image data …
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Nanostructured apatites as orthopedic biomaterials
… that most failures involved an unstable implant-tissue interface and/or a mismatch of the mechanical behavior of the implant with the surrounding tissues. As a result, up to 20% of patients receiving permanent, load-bearing implants may undergo a revision operation. The objective of this research …
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Microwave Hydration Monitoring Using Wearable Antennas
… antennas designed for microwave-based localized tissue assessment at the extremities to detect hydration changes. A conformal printed monopole antenna, operating over a wide frequency range, is developed on denim fabric, and its performance is analyzed both in air and in contact with lossy …
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MICROELECTRODE ARRAY FOR CAPACITIVE TRANSDUCTION OF RETINAL RESPONSES
… motivating the development of neural prosthetic interfaces to restore sensory or motor function in affected individuals. Advances in neural sensing and stimulation interface technology will allow a more comprehensive understanding of neural function while leading to the development of hybrid …
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Design and development of a fluid actuated neural probe for chronic sensing
… brain dysfunction for brain-machine interfaces and in neuroscience studies for interrogation of neural tissue. The performance of implantable neural probes for chronic applications has been hampered, owing to an inflammatory immune response in the vicinity of the implanted devices, …
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A system for impedance characterization of coronary stents
… out to monitor endothelialisation of the stent-tissue interface using invasive methods, but such methods are commonly only suitable for in vitro studies (Prasad et al, 2005), meaning they cannot be practically used clinically and can only provide information at a limited number of time points. …
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Cells, surfaces and adhesion
… maintenance of normal matrix production at the tissue interface.
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High-Voltage Compliant, Electrode-Invariant Neural Stimulation Electronics Compatible with Low-Voltage, Bulk-CMOS Integration
… practical, electrical neural stimulation interfaces using modern silicon CMOS technologies. To overcome said challenges, which stem from the discrepancy between the low-voltage limitations of modern CMOS devices and the large stimulation voltages often observed at response-evoking stimulus …
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Fast Neuronal Imaging using Objective Coupled Planar Illumination Microscopy
… by enhancing the spatial resolution deeper in tissue.</italic> Tissue inhomogeneity and refractive index mismatch at the surface of the tissue lead to optical aberrations. We have compensated for such aberrations by: 1) miniaturizing the OCPI illumination optics, so as to enable more vertical …
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Identification of Image-based Markers for Oral Pre-cancers and Cancers using in-vivo Multimodal Imaging
… on visual conventional oral examination of oral tissue surface with palpation to guide biopsy as subtle alterations often occur in early neoplasia, despite subsurface cellular and molecular alterations that are known to occur. Robust noninvasive methods are needed with improved performance to …
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Utility of the Visible Heart® and Micro-CT Imaging to Optimize the Treatments of Bifurcation Stenting
… which then allows for post implant device/tissue interface analyses. Utilizing reanimated swine hearts, we were able to uniquely visualize how the various bifurcation techniques performed could be optimized in specific anatomies. These findings again confirm that the Visible Heart® …
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Development of a biomechanical model of the interface between the residual limb and prosthesis for trans-femoral amputees
… behaviour at the residual limb / socket interface for the purpose of obtaining a quantitative evaluation of socket fit. Three dimensional FE models of the residual limb of trans-femoral amputees were generated based on geometrical data obtained using a mechanical digitizer and magnetic …
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Reduction of Dose Calculation Errors For Patients With Metal Implants Receiving Photon Radiation Therapy
… dose calculation algorithms in modeling metal/tissue interface effects. Metals also cause streak artifacts in the computed tomography (CT) images that are used for treatment planning, and these artifacts can also degrade dose calculation accuracy. Metal based-energy deposition kernels are a …
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Effects of Dip-coated films on the Properties of Implantable Intracortical Microelectrodes
… and paralysis is limited by a reactive tissue response (RTR) of the brain. This RTR culminates in the formation of a tight glial scar and a loss of neuronal density around implanted ICMs, and is accompanied by a decrease in signal to noise ratio and an increase in impedance. While no …
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An implantable micro-system for neural prosthesis control and sensory feedback restoration in amputees
… the prototype of an electronic bi-directional interface between the Peripheral Nervous System (PNS) and a neuro-controlled hand prosthesis is presented. The system is composed of two Integrated Circuits (ICs): a standard CMOS device for neural recording and a High Voltage (HV) CMOS device for …
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The application of FEM technique to electromagnetic models for magnetic neural stimulation
… 1) magnetic coil diameter, 2) anisotropic tissue conductivity, 3) inhomogeneous tissue conductivity and 4) finite tissue volumes. All results are analyzed in terms of the second space derivative of the potential along the nerve fiber path 82V/82 called the "activation function". If two …
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