Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"sequence effects"”.
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Sequence Effects and Ligand Selectivity in Targeting Non-Canonical DNA Structures
… DNA structure that can occur in G-rich DNA sequences. These structures, which are compact and diverse, have been implicated in a wide range of processes including telomere maintenance, transcriptional control, and DNA replication and repair. In order to target specific G4 structures, and …
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Studying sequence effects of mRNA 5' cap juxtapositions on translation initiation rate using randomization strategy of the extreme 5' end of mRNA
… where the role of 5’ cap proximal mRNA sequence determinants are poorly understood. To explore the effect of the nucleotides in the extreme 5’ end of mRNA on translation initiation, a library of mRNA molecules was synthesized containing all possible permutations of the first 10 …
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A Comparison of Discounting Parameters Obtained Through Two Different Adjusting Procedures: Bisection and Up-Down.
… outcomes. One involved adjustments using a fixed sequence of ascending or descending amounts, the other used a bisection algorithm in which the changes in amounts varied as a function of the subjects' choices. Two magnitudes of delayed outcomes were used: $1,000 and $10,000. A within subject …
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Theory of pattern and pH effects in complex coacervation
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2023-12-04 without embargo terms
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Cognitive Differentiation of Schizophrenia and Depression
… emerged as a function of diagnosis and stimulus sequence. All three groups showed intact auditory sensory memory, with comparable amplitudes and sequence effects. Schizophrenics did not differ from controls overall, but, in analyses as a function of diagnostic subtype, MMN was reduced in paranoid …
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Finite element analysis of anisotropic viscoelastic composite structures and analytical determination of optimum viscoelastic material properties
… ply laminates are calculated and the stacking sequence effects of the laminates are discussed in detail. Creep responses for GY70/339 composite laminates with or without a circular hole are also studied. The numerical results compare favorably with analytical solutions, i.e. within 1.8% for …
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Flexural Stiffnesses of and Dimensional Stability in Circular Quasi-isotropic Laminate Mirrors
… constraints, and lack of understanding for effects of resin buffer layers on composite mirrors for high surface smoothness. In this dissertation document, radial stiffness associated with stacking sequence effects in quasi-isotropic laminates (pi/n, where n=3, 4, and 6) and dimensional …
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Noncovalent adsorption of nucleotides in gold nanoparticle DNA conjugates : bioavailability at the bio-nano interface
… report a systematic study of the effect of DNA sequence on the binding interaction between gold nanoparticles and thiolated DNA (AuNp-DNA). Base specific noncovalent nucleotide adsorption on gold surfaces can affect nucleotide bioavailability in solution. Systematic investigation of DNA …
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Can Teaching Flexible Relational Responding Result in Improved Ability Scores in Children with Diagnosed Autism?
… design which is not subject to problematic sequence effects that may result with multiple baseline design. Cassidy, Roche, & Hayes, (2011) found that a teaching complex forms of relational responding resulted in significant gains in cognitive ability as measured by IQ tests. The current …
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The effect of physical molecular features on complex coacervation phase separation
… in entropy. Additionally, precise charge sequence effects can be captured using this transfer matrix theory. Initial simulations demonstrated that the periodicity of the charge sequence affects counterion entropy gain, which is the entropy counterions gain upon being released from a …
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Crop Rotations for Sustainable Intensification
… weather conditions. Nevertheless, crop sequence effects were clearly detectable, particularly in winter crops and under low to moderate N fertilization levels. Diversified crop rotations that included non-cereal crops, catch crops, and spring-sown crops improved NUE, yield stability, and …
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Thermodynamic Interactions in Polydiene/Polyolefin Blends
… proposed to originate from non-random mixing effects in the enthalpic contribution to the interaction parameters, which are not included in the theory. Blends were also examined containing random copolymers of polydienes and polyolefins, in order to modulate the large polydiene/polyolefin …
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Self-healing and ionic interactions: a look into thermal properties of sequence-specific ionic networks and the synthesis of spiropyran monomers for triggerd ionic networks
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2016-11-09 without embargo terms
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DNA-Protein Cross-links: Formation, Repair, and Inhibition of DNA replication
… However, the understanding of cellular effects on DPCs is not fully understood. The main objective of this thesis was to investigate the effects of DPCs on replication, as well as elucidate mechanisms of repair.In Chapter II, we investigated the local DNA sequence effects on TLS …
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Targeting Alternative Conformational States of the HIV-1 Rev Response Element Stem IIB using Small Molecules
… to restore the GS conformation and control for sequence effects. We then demonstrate that the degree to which increasing the population of the ES at the expense of the GS leads to a corresponding decrease in cellular activity. The results also support that stabilizing non-native ESs potentially …
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The Effects of Resistant Starch Intake in African-American Americans at Increased Risk for Type 2 Diabetes
… ± 0.18% and 6.9% ± 0.14% at baseline for the sequence groups, resistant starch first (n=7) and control treatment first (n=8) groups, respectively. Mean± standard error HbA1c values were 6.7%± 0.27% and 6.9% ± 0.27% at the conclusion of fourteen-week study for sequence groups, resistant starch …