Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 118 for “"scarring"”.
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TARGETING FIBROBLAST-MATRIX INTERACTIONS TO TREAT VOCAL FOLD SCARRING
… voice, after laryngeal injury is vocal fold (VF) scarring, which typically follows upper airway trauma or iatrogenic injury. After initial VF damage, immune cells infiltrate the wound bed and secrete various cytokines, including transforming growth factor-β (TGF-β), to promote tissue repair. In …
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Self-esteem and Body Image Changes in Adolescents After Scarring Surgery
… by a surgical procedure that causes visible scarring.<br> 2. How body image in adolescents changes over time when interrupted by a surgical procedure that causes visible scarring.<br> 3. How the relationship of body image and self-esteem change over the course of surgical intervention.<br> 4. …
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Developing a Drug Delivery System for Treatment of Vocal Fold Scarring
<p>Vocal fold scarring is an affliction that results in the formation of a disorganized and stiff extracellular matrix (ECM) with abnormal ECM component densities & structures including a significant increase in collagen deposition. It is caused by improper healing post injury and results in …
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The effects of an artificial skin on scarring and contraction in open wounds
Thesis (Ph.D.)--Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1983.
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An analysis of the determinants and scarring effects of economic inactivity and unemployment in the UK
This thesis aims to analyse the determinants and scarring effects phenomenon of economic inactivity and unemployment – NEET (Not in Education, Employment or Training) – in the UK. We are particularly interested in examining the impacts of different business cycle periods and investigate the …
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An investigation into the use of a clear coat sublayer on concrete surfaces to prevent scarring
… urethane provided good resistance against scarring due to increased penetration of the adhesive, indicating potential for the idea. Furthermore, the use of multiple sublayers proved ineffective at improving the scarring resistance of concrete.
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Relationships among spread-sticker application, blossom cap retention, berry scarring, thrips populations, and Botrytis bunch rot in 'Chardonnay' grapes, and a survey of pesticide use and pest severity in Virginia vineyards in 1990 and 1991
… pressurized air. Cap and debris retention, berry scarring, and Botrytis rot were evaluated throughout the season. The spreader-sticker application increased debris retention only slightly. Removal of caps and debris had no effect on scarring, but reduced Botrytis bunch rot. The role of flower …
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Characterization of the vocal fold lamina propria towards voice restoration
… this complex biomechanical system is reduced by scarring, voice quality may be compromised. Currently, little can be done to treat patients affected with voice loss or chronic voice impairment due to scarring. Because of the size of the patient population suffering from voice impairment secondary …
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Comparative histology of human skin.
… to assess if dermal structure correlates with scarring potential. (iv) Skin samples were sectioned in a plane parallel to the epidermis to gain further insight into dermal structure. (v) A novel basement membrane stain was produced. Type I and type III collagen are important structural …
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Development of a novel co-culture based in vitro model system to study the wound healing process
… due to the complex nature of wound healing and scarring processes and the limitations of available in vitro or in vivo models used for preclinical drug testing. Many patients who undergo elective back surgery develop post-surgical complications resulting from excess peridural scarring in and …
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Characterisation of Cutaneous Wound Healing Process in Naked Mole Rats
… analysis revealed characteristics of reduced scarring in NMR wounds including low collagen I to III ratio, increased HA expression (HMW) and increased fibronectin expression. Transcriptional profiling of TGFβ isoforms and different pro/anti-inflammatory cytokines revealed a balance in the …
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QUANTIFYING CURRENT SOIL BRINE CONTAMINATION WITHIN THE SMACKOVER OIL FIELD IN ARKANSAS USING MULTISPECTRAL DIGITAL IMAGERY
… of brine in the oil field created landscape scarring across the study area.</p> <p>Landsat 9 multispectral digital imagery was utilized to create supervised classification maps based on earthen pits and creek scarring across the Smackover Oil Field. The results from these maps were compared …
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The Bony pelvis scars of parturition and factors Influencing their manifestation
… on the pelvis reported to display parturition scarring in a skeletal sample of 391 individuals (230 males and 161 females). The scar features, body and pelvic dimensions were compared according to the sex, age and time period of origin of the individuals. Correlation tests were performed to …
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A new surgical model or studying the healing response of renal tissue in the presence of collagen-glycosaminoglycan matrices
… of part of a patient's kidney, which leads to scarring, distortion of the renal architecture, and potentially renal insufficiency. Current research suggests that the implantation of collagen-glycosaminoglycan (GAG) extra-cellular matrices after traumatic renal injury prevents contraction, …
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Innate immunity in defence against infection and tissue repair of the urinary tract
… in acute pyelonephritis and infection-mediated scarring. Here, we identify type 17 immune response genes amongst the most up-regulated networks in the mouse bladder following UPEC challenge and identified ILC3s as a major source of these cytokines. Depletion of ILCs in Rag2-/- mice resulted in …
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The trauma and narratives of adult burn survivors : a South African perspective
… recovery from the injury, as well as their scarring and disfigurement. It was found that the experience and understanding of the trauma was created and maintained on a social level through norms and values, interpersonally through interactions with other people, as well as through the …
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Bioenergetic Evaluation of Site-specific Keloid and FKN Fibroblasts
Excessive scarring due to fibrosis from aberrant wound healing can lead to conditions such as Keloids or Folliculitis Keloidalis Nuchae (FKN). These fibroproliferative growths pose therapeutic challenges due to their complex aetiology that has been linked to multiple genetic and environmental …
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Spinal cord regression via collagen entubulation
… scar formation in Groups I and III, less fibrous scarring in Group II and very little scar manifesting in Groups IV and V. A quantitative analysis of myelinated axons in the center of the explants corresponded with the assessment of scar as a physical barrier to competent axon growth. Groups I and …
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Computational Modeling and Simulation Study of Dermal Wound Healing Proliferative Phase
… healing such as chronic wounds or excessive scarring. Mathematical modeling has been used to investigate many aspects of wound healing. Angiogenesis is pertinent for dermal wound healing since the cellular activities involved in tissue repair requires oxygen and nutrients to be delivered to …
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Mechanism of Metformin Action in Dermal Fibroblasts
… wound healing rates, potentially decreasing scarring. Alternatives to insulin therapy include biguanide drugs such as metformin. Metformin downregulates gluconeogenesis, and reduces blood glucose levels by activating glucose transport via GLUT4 in muscle cells. Importantly metformin has been …
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