Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"sFRP1"”.
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Control of proliferation in human mesenchymal stem cells by Secreted Frizzled Related Protein 1
… except Wnt11. Especially, gene expression of sFRP1, an antagonist of Wnt signaling, was also decreased. To confirm whether sFRP1 affects proliferation of hMSC, MSC/sFRP1 and MSC/shsFRP1 were made and then cell proliferation was measured. Growth kinetics result showed that sFRP1 could affect …
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Role of Wnt signaling in proliferation of human bone marrow-derived mesenchymal stem cells
… but nuclear β-catenin level was not related to sFRP1. Interestingly, specific knockdown of sFRP1 by shRNA in hMSCs decreased their proliferation rate, whereas recombinant sFRP1 protein accelerates the growth of cells. These findings suggest that sFRP1 has a pivotal role in proliferation of hMSCs …
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Mikroglia fördert die Invasivität von Karzinomzellen
… durch die Wnt-spezifischen Inhibitoren Dkk-1 und sFRP1 partiell hemmbar, was für eine Aktivierung des Wnt-Signaling im Rahmen der proinvasiven Effekte spricht. Im Gegensatz zu den peripheren Makrophagen fördert die Mikroglia die Tumorprogression ohne direkte Induktion von Wnt 5a, das bereits …
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Identifizierung und Charakterisierung von Genen für die Entwicklung der Nieren und des Urogenitalsystems
… Gewebe, die mit den Expressionsmustern von sFRP1 und sFRP4 verglichen wurde. Die detailierte Genexpressionsanalyse der sFRP-Familie in der murinen Embryonalentwicklung sollte als Grundlage für funktionelle Studien dieser erst kürzlich entdeckten neuen Genfamilie dienen. Erste Untersuchungen …
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Epigenetic modifications on WNT genes by dietary genistein during colon cancer development
… of WNT signaling genes including Wnt5a, Sfrp1, Sfrp2, and Sfrp5 to the similar level to that of pre-AOM period. Rats fed SPI and GEN had a decreased number of total aberrant crypts. GEN feeding also resulted in a reduced number of ACF with N=3 per foci. The reduction of WNT/β-catenin …