Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 907 for “"prostate"”.
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Transcatheter Arterial Embolization of Prostate in Hormone Induced Canine Prostate Hyperplasia
PURPOSE: Benign prostate hyperplasia (BPH) is the most common reason for surgical intervention among elderly men. Currently, main treatment modalities are medication and transurethral resection of the prostate (TURP) which is considered as the gold standard for the surgical management of …
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Microrna Regulation of Prostate Cancer Stem/Progenitor Cells and Prostate Cancer Development
… miRNA expression profiling in six populations of prostate cancer (PCa) stem/progenitor cells that possess distinct tumorigenic properties. Six miRNAs were identified to be commonly and differentially expressed, namely, four miRNAs (miR-34a, let-7b, miR-106a and miR-141) were under-expressed, and …
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The role of tomato and lycopene consumption on prostate carcinogenesis and prostate cancer treatment
Prostate cancer (PCa) is most commonly diagnosed cancer among men in the United States. Following PCa diagnosis, men often seek information about foods and supplements that may improve their response to therapies, quality of life and survival. Tomatoes and their primary bioactive (lycopene) are one …
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Nanotherapies for Treating Prostate Cancer
<p>Current prostate cancer treatment remains ineffective primarily due to ineffectual therapeutic strategies and numerous tumor-associated physiological barriers which hinder efficacy of anticancer agents. Therefore, the focus of this study was to investigate a new combination therapy approach for …
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Improving Quality of Prostate MRI
Prostate cancer (PCa) is the most common cancer among men in the UK and the second leading cause of cancer-related deaths in men worldwide, with its incidence expected to double by 2040. Chapter 1 of this thesis explored the anatomy of the prostate gland, epidemiology, classification, and grading …
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Prostate-specific Antigen Nadir and Time to Prostate-specific Antigen Nadir Following Maximal Androgen Blockade Independently Predict the Prognosis in Patients with Metastatic Prostate Cancer
PURPOSE: To evaluate the influence of prostate-specific antigen (PSA) kinetics following maximal androgen blockade (MAB) on the disease progression and cancer-specific survival in patients with metastatic, hormone sensitive prostate cancer. MATERIALS AND METHODS: One hundred thirty-one patients …
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The accuracy of prostate biopsy to assign patients with low-grade prostate cancer to active surveillance
PURPOSE: To determine the accuracy of prostate biopsy Gleason score (GS) compared to prostatectomy GS. To determine whether a biopsy is a satisfactory diagnostic procedure to offer active surveillance for patients with low-grade prostate cancer. METHODS: This study was conducted in Tuft Medical …
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Adaptive Radiation Therapy Of Prostate Cancer
… This retrospective study evaluated ART for prostate cancer treatment and radiobiological consequences. An IRB approved protocol has been used to evaluate actual dose delivery of patients with prostate cancer undergoing treatment with daily CBCT.</p> <p>The dose from CBCT was measured in …
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Prostate cancer recognition in ultrasound images
Our purpose is to aid medical doctors in prostate cancer detection via computer automated analysis of prostatic ultrasound imagery. Absorption of ultrasound signals is different in cancerous areas than in non-cancerous areas. The energy of the signal, the continuity of the signal, the …
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Modelling geometric uncertainties in prostate radiotherapy
… onthe tumour control probability (TCP) for prostate radiotherapy is investigated.Positional measurement data are analysed in a manner which differentiates betweengenuine measured variation and measurement uncertainty. A deformable model of theprostate is developed which encompasses …
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Molecular diagnosis in prostate cancer. PCA3.
Contains fulltext : 74427.pdf (Publisher’s version ) (Open Access)
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Role of Wnt5a in Prostate Cancer
… upregulated at both mRNA and protein levels in prostate cancer, but information regarding its role in predicting clinical outcome in patients after radical prostatectomy is limited. The aim of the present thesis is to define the role of Wnt5a protein expression in prostate cancer. We started by …
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Tomato Phytochemicals and Prostate Cancer Risk
… in tomato cell suspension cultures. DU 145 prostate tumor cells absorbed 14C-15- cis phytoene and an oxidized phytoene product and partially metabolized these compounds in vitro. To elucidate the biological roles of phytoene and phytofluene, it was essential to determine the biodistribution …
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Testosterone, Lycopene Isomers, and Prostate Cancer
… (NMU)-testosterone-induced prostate cancer in rats. Survival was analyzed to include only rats that died with adenocarcinomas of the accessory sex glands. Only tomato powder-fed (RR = 0.570; P = 0.009) rats experienced significantly increased survival as compared to placebo …
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Estrogen receptor beta modulates prostate carcinogenesis
Prostate cancer (PC) is characterised by dependence upon androgen receptor (AR) as its driving oncogene. When organ-confined, radical treatment can be curative, however there is no cure for advanced, castration-resistant prostate cancer (CRPC). There is therefore a need to better understand the …
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Modeling recovery curves for prostate cancer
… for patients following 3 different forms of prostate cancer treatment. I propose a parametric model for those function level time series and show promise that the method can be applied to both simulated and real data.
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Chemosensory Evaluation of Prostate Cancer Cells
Prostate cancer is the most commonly diagnosed disease and second most commonly caused death among men in America. Although much controversy surrounds the current methods of detection, PSA test and biopsy, no new methods have been approved as an effective method of detection. Biomarkers and …
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Characterising the mechanism of DCUN1D1 activity in prostate cancer and identifying DCUN1D1 inhibitors for prostate cancer treatment
… in our lab demonstrated the role of DCUN1D1 in prostate cancer in vitro and in vivo. We also identified potential inhibitors of DCUN1D1 which inhibited the proliferation of prostate cancer cells in a DCUN1D1-specific manner. This study seeks to determine the mechanism of action of DCUN1D1 in …
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Characterising the mechanism of DCUN1D1 activity in prostate cancer and identifying DCUN1D1 inhibitors for prostate cancer treatment
… in our lab demonstrated the role of DCUN1D1 in prostate cancer in vitro and in vivo. We also identified potential inhibitors of DCUN1D1 which inhibited the proliferation of prostate cancer cells in a DCUN1D1-specific manner. This study seeks to determine the mechanism of action of DCUN1D1 in …
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