Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"postconditioning"”.
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Cardiovascular Risk, Remote Ischemic Postconditioning, and Endothelial Ischemia-Reperfusion Injury
<p>Remote ischemic postconditioning (rIpost) is a potent vasculoprotective stimulus that is thought to reduce reperfusion injury associated with heart disease. However, certain animal models of cardiometabolic risk factors such as dyslipidemia, diabetes, and hypertension suggest the beneficial …
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Role of Tumour Necrosis Factor Alpha (TNFa) in ischaemic and pharmacological postconditioning
Ischaemic postconditioning (IPostC) is a powerful protective mechanism that activates prosurvival intrinsic signalling cascades to limit reperfusion injury but the exact signalling pathway involved in this cardioprotective effect still remains unclear.
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Cardioprotective role of signal transducer activator of transcription 3 (STAT-3) against ischaemai reperfusion injuries
… Both S1P preconditioning and ischaemic postconditioning reduce myocardial damage following an ischaemia-reperfusion insult but the mechanisms involved remain unclear. Janus kinase/Signal transducer and activator of transcription 3 (JAK/STAT-3) form part of a recently discovered powerful …
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The role of signal transducer and activator of transcription-3 (STAT-3) in ischaemic and pharmacological postconditioning
Includes abstract. Includes bibliographical references (leaves 131-147).
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Adaptive Mechanisms of the Heart to Ischaemic Stress
… transmural flow heterogeneity. The data from the postconditioning study did not show a difference in infarct size between the groups but numbers were small.<br/>Conclusion<br/>The mechanisms of adaptation of the heart to ischaemic stress are complex and likely multifactorial. These results suggest …
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Effect of Isoflurane Post-treatment on tPA-exaggerated Brain Injury in a Rat Ischemic Stroke Model
Intravenous tissue-type plasminogen activator (tPA) is recognized as the standard treatment for ischemic stroke. However, its narrow therapeutic window and association with an increased risk of intracranial hemorrhage have required caution when used. In this context, several approaches are required …
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Kardioprotektion durch Postkonditionierung gesunder Rattenherzen sowie von Herzen mit kardiovaskulären Risikofaktoren: Charakterisierung der Signaltransduktion unter besonderer Betrachtung von PI3-K/Akt, mTOR, ERK1/2 und GSK-3ß
In den ersten Versuchsreihen der hier vorliegenden Arbeit bestätigte sich, dass im in vitro Modell die klassische ischämische Präkonditionierung kardioprotektiv wirkt. Die Präkonditionierung bewirkte eine Infarktgrößenreduktion um 54 %; dies wird durch Literaturangaben bestätigt. Die …