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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 24 for “"neurological dysfunction"”.

  1. The Relationship between Cobalamin Deficiency and Neurological Dysfunction in Older Adults

    Bachra, Marion

    … Persistent Cbl deficiency can cause a variety of neurological deficits. Neurological dysfunction occurs commonly among older adults, raising the research question whether or not there is a relationship between the high prevalence of Cbl deficiency and neurological dysfunction among older …

    loma-linda Repository record

  2. Feasibility of Assessing an Infant's General Movements Using Wireless Accelerometers for Early Diagnosis of Neurological Dysfunction

    Dillon, Travis EricVirginia Tech2005

    … or the lack of, are an accurate way diagnosing a neurological dysfunction in the early stages of infancy. One study has shown that definitely abnormal movements occurring between 10-20 weeks post-term accurately predicted cerebral palsy in infants with an accuracy of 85 to 98 percent [1]. The …

    vt Repository record

  3. Genetically-programmed suicide of adrenergic cells in the mouse leads to severe left ventricular dysfunction, impaired weight gain, and symptoms of neurological dysfunction

    Owji, Aaron

    … cells are required for normal cardiovascular and neurological function. To genetically ablate adrenergic cells, we mated Pnmt-Cre mice, in which Cre-recombinase is under the transcriptional regulation of the Pnmt promoter, and a Cre -activated diphtheria toxin A (DTA) mouse strain …

    ucf

  4. Adult neoplastic spinal cord compression

    Pillay, RobinDivision of Neurosurgery2000

    Spinal cord compression ( SCC ) constitutes a neurological emergency, and if left untreated, can result in permanent irreversible neurological dysfunction. Disabilities can range from mild weakness to complete quadriplegia with the inherent associated mental, physical and emotional suffering .The …

    cape-town Repository record

  5. Synaptic morphology, function, and regulation in a paediatric-onset neurodegenerative disorder

    Shoubridge, Andrew Peter2021

    … accumulates within lysosomes as a result of dysfunctional lysosomal protein. The most common sub-group is mucopolysaccharidosis (MPS) III (collectively 1 in 70,000). In Australia, MPS IIIA is the most common sub-type and the focus of this study. MPS IIIA is caused by an autosomal recessive …

    adelaide Repository record

  6. Neuropsychological symptoms in the learning disabled child : a symptomology inventory

    West, Penny L.1990

    A predominance of symptomology related to neurological dysfunction has been reported for at least some learning disabled (LD) students. This investigation examined the self-reported neuropsychological symptoms of LD and normal students in grades 3 through 12. Determination of group membership based …

    ballstate-thes Repository record

  7. Unique variability between the Dean-Woodcock Emotional Status Examination and the MMPI

    Morse, Megan M.2013

    … the comorbid psychiatric symptoms present in neurological disorders and psychiatric symptoms has grown exponentially over the past decade. A number of authors have argued in favor of the biological basis of psychiatric symptoms and the interaction with neurological dysfunction (Noggle & Dean, …

    ballstate-thes Repository record

  8. Towards Data-Driven Cognitive Disease Classification using Machine Learning and the Digital Symbol Digit Test

    Kim, EvanMassachusetts Institute of Technology2022

    … slow disease progression. Early detection of neurological dysfunction is often caught through screening tests like the Symbol Digit Test. Researchers at MIT and Lahey have been administering the Symbol Digit Learning Test using a digitizing pen that records data and pen strokes made by …

    mit Repository record

  9. Using Accelerometers to Quantify Infant General Movements as a Tool for Assessing Motility to Assist in Making a Diagnosis of Cerebral Palsy

    Conover, Mark StuartVirginia Tech2003

    … nor been used effectively in evaluating neurological dysfunctions' affect on movement. This thesis presents a new quantitative technique for measuring infant general movements (GMs) using micro-electromechanical accelerometers, while discussing future improvements for this technology and …

    vt Repository record

  10. Characterizing the Cellular Response to Astrovirus Infection in the Central Nervous System

    Davis, Amy E.2025

    … health challenges, often leading to severe neurological dysfunction with high morbidity and mortality rates. Astroviruses (AstVs), traditionally known for causing gastroenteritis, have recently been identified as neuroinvasive pathogens capable of inducing neurological diseases. This study …

    tenn-hsc Repository record

  11. Changes in the Oligodendrocyte Progenitor Cell Nuclear Lamina During Ageing

    Fleet, AlexanderUniversity of Cambridge2024

    … leading to neurodegeneration and progressive neurological dysfunction in older individuals with MS. Therefore, understanding the mechanisms of OPC ageing, and how these mechanisms might be slowed or reversed, is imperative in the search for new therapies for demyelinating diseases, with the …

    cambridge Repository record

  12. Generation of a Medaka Fish Model of Propionic Acidemia for Development of Novel Therapies.

    Ginocchio, Virginia MariaThe Open University2016

    … also suffer from multi-organ complications, neurological dysfunction, and cardiomyopathy. Despite available treatments, disease mortality and morbidity remain elevated and investigation of novel and more effective therapies is highly needed. <br></br><br></br> I have generated a PA model in …

    the-open-u Repository record

  13. Neurologic And Metabolic Safety Of Fluoroquinolones

    Ellis, Darcy2021

    … 1, the outcomes of interest were CNS and PNS dysfunction. Cox proportional hazards models were estimated after matching. The hazard ratio associated with fluoroquinolone exposure was 1.08 (95% confidence interval [CI]: 1.05-1.11) for CNS dysfunction, and 1.09 (95% CI: 1.07-1.11) for PNS …

    penn Repository record

  14. Chronic low-level Pb exposure during development alters proteins involved in energy metabolism in auditory neurons of the brainstem

    Prins, John

    Low level lead (Pb) exposure is a risk factor for neurological dysfunction including ADHD. How Pb produces these behavioral deficits is unknown, but low-level exposure during development is associated with auditory temporal processing deficits, even though hearing remains normal. Pb disrupts …

    montana-tech Repository record

  15. Chronic low-level Pb exposure during development alters proteins involved in energy metabolism in auditory neurons of the brainstem

    Prins, John

    Low level lead (Pb) exposure is a risk factor for neurological dysfunction including ADHD. How Pb produces these behavioral deficits is unknown, but low-level exposure during development is associated with auditory temporal processing deficits, even though hearing remains normal. Pb disrupts …

    montana Repository record

  16. Upregulation of Reactive Oxygen Species During The Retrovirus Life Cycle and Their Roles In A Mutant of Moloney Murine Leukemia Virus, Ts1-Mediated Neurodegeneration

    KIM, SOO JIN2011

    … central nervous system (CNS) and development of neurological symptoms is a characteristic of many retroviruses. The mechanism by which retrovirus infection causes neurological dysfunction has yet to be fully elucidated. Given the complexity of the retrovirus-mediated neuropathogenesis, studies …

    uthsc Repository record

  17. ECMO Therapy in Intensive Care Settings: A Global Perspective on Outcomes and Observational Practices – Examining Factors Associated With ECMO Survival

    Aldajani, Shuaa2028

    … ECMO-related complications (infection, renal dysfunction, neurological dysfunction), and time to ECMO initiation were also significantly associated with mortality, with<em> p </em>< .05. Regression analysis with ECMO-related complications (infection, renal, neurological) and time to ECMO …

    usd-thes Repository record

  18. DNA Damage Induction by Bilirubin Induced Oxidative Stress and Activation of DNA Repair Pathways by Bilirubin

    Rawat, Vipin SinghThe Open University2018

    … if not promptly treated. Bilirubin causes severe neurological dysfunction by affecting several different cellular pathways such as, induction of oxidative stress, endoplasmic reticulum (ER) stress, autophagy, neuroinflammation and DNA damage. The work done in this thesis focus on the DNA damaging …

    the-open-u Repository record

  19. Characterisation of a novel Rab18 mouse model for Warburg Micro syndrome

    Carpanini, Sarah MarieThe University of Edinburgh2014

    … by abnormalities affecting the ocular, neurological and endocrine systems. Previous studies have identified causative loss-of-function mutations in four members of the RAB protein network; RAB3GAP1, RAB3GAP2, RAB18 and TBC1D20, causing clinically indistinguishable phenotypes. RAB3GAP1 …

    edinburgh Repository record

  20. The Bender Gestalt and Symbol Digit Modalities Tests as Cerebral Dysfunction Screening Instruments :a Comparative Evaluation

    Wright, Bruce R

    … psychological tests as screening instruments for neurological dysfunction in a large and varied institutional population.</p> <p>Method</p> <p>The Bender Visual-Motor Gestalt Test (BGT) and Symbol Digit Modalities Test (SDMT) were administered to one hundred incarcerated males from four …

    andrews-thes Repository record

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