Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 17 of 17 for “"membrane capacitance"”.
-
Comparison of the sodium ion channel densities, the water flux changes, and the membrane capacitance changes in the pelvic and pectoral skin of the toad, Bufo woodhousei
… region of the toad, Bufo woodhousei. The apical membrane capacitance (C{dollar}\sb{\rm a}{dollar}) of the cells in the stratum granulosum of neither skin region was changed by AVT treatment when an osmotic gradient was present across the tissue; Short circuit current (I{dollar}\sb{\rm …
-
The Impact of Calcium Binding Protein 5 (CaBP5) on Synaptic Vesicle Dynamics in Rod Bipolar Cells in the Retina
… release at the presynaptic RBC terminals. Using membrane capacitance measurements in the acutely isolated RBCs, we found that the total number of fusion-competent vesicles in RBCs was not different between CaBP5⁻/⁻ and wild-type mice. However, CaBP5-/- RBCs showed a greater rise in membrane …
-
Particle Manipulation Using Electric Field Gradients in Microdevices
… selectivity and to determine an estimated membrane capacitance for each. From the results, the membrane capacitance of the early to intermediate stages proved to be very similar; however, late stage breast cancer cells have potential in being separated from early and intermediate stages.
-
Contactless Dielectrophoresis towards Drug Screening and Microdevice Development for Cell Sorting
… to extract the crossover frequency and specific membrane capacitance of early and late stage mouse ovarian surface epithelial (MOSE-E and MOSE-L) cells when untreated, treated with the anti-cancer sphingosine (So) metabolite and with a generally cancer-supporting sphingosine-1-phosphate (S1P) …
-
INFRARED NEURAL STIMULATION AND FUNCTIONALRECRUITMENT OF THE PERIPHERAL NERVE
… Intracellular currents generated by changes in membrane capacitance or intracellular calcium release were hypothesized capable of triggering action potentials under conditions determined physiologically possible. Results show that activation with membrane capacitance changes depend on the …
-
Nanoparticle-Based Drug Delivery and the Impacts on Cancer Cell Biophysical Markers
… and a significant decrease in specific membrane capacitance. Furthermore, SphKI-treated cells became slightly more deformable as measured by a decrease in their channel entry and travel times. We observed no significant difference in the bioelectrical changes produced by SphKI delivered …
-
Electrohydrodynamic Simulations of Capsule Deformation Using a Dual Time-Stepping Lattice Boltzmann Scheme
<p>Capsules are fluid-filled, elastic membranes that serve as a useful model for synthetic and biological membranes. One prominent application of capsules is their use in modeling the response of red blood cells to external forces. These models can be used to study the cell’s material properties …
-
Silicon nanopore patch clamp device for measuring single ion channel activity
… seal between a glass micropipette and a cell membrane. This transformative method allows low noise recording of current arising from single ion channels or from an entire cell and has no equivalent in experimental neuroscience. However, the consistent formation and maintenance of a high …
-
Measurement and Analysis of Calcium-Dependent Exocytosis in Giant Excised Membrane Patches
… emphasis on the rat secretory cell line, RBL. Capacitance and amperometric recordings show that secretory granules (SGs) containing serotonin are mostly lost from excised patches. Small vesicles that are retained (non-SGs) do not contain substances detected by amperometry. Non-SG fusion is …
-
Nature of Large Vesicle Exocytosis in Pancreatic β-cells: Release of ATP and GABA
… techniques such as measurements of cell membrane capacitance and amperometry are used to detect exocytotic events. A novel method was developed in this study based on the expression of P2X2 receptor channel in secreting cells. The presence of ATP sensitive channel on the cell membrane …
-
Investigating Synapse Function In Organotypic Hippocampal Slice Culture Models of Neurodegeneration
… accompanied by significant decreases in membrane capacitance. Ablation of microglia in these cultures partially recovered LPS induced synaptophysin loss, but did not recover functional deficits. These results provide insight into how best OHSCs should be used as a tool to explore …
-
Design and Optimization of Temporal Encoders using Integrate-and-Fire and Leaky Integrate-and-Fire Neurons
… The LIF neuron is able to use a smaller membrane capacitance to achieve similar operability as the IF neuron and consumes less area despite having more components. This demonstrates that capacitor sizes are the main limitations of a small size in spiking neurons for SNNs. An overview of …
-
Frequency Selectivity of Synaptic Exocytosis in Hair Cells of the Bullfrog's Amphibian Papilla
… dependence of the traveling waves on the basilar membrane, the flexible structure that houses hair cells, the auditory receptors. However, in non-mammalian vertebrates, the basilar membrane does not conduct a traveling wave. In some animals, the membrane is absent entirely. Yet auditory fibers …
-
Dielectric Relaxation Processes at Apical Membranes of Frog Skin: Changes of Capacitance and Sodium Ion Channel Density
… the capacitive properties of their apical plasma membranes and to determine whether vesicle fusion is the likely mechanism for the regulation of apical Na$\sp+$-channel density. Experiments were done in the presence of 100 $\mu$M amiloride and Na$\sp+$-free apical Ringer solution. This procedure …
-
Effects of Ca2+, microRNAs, and rosuvastatin on insulin-secreting beta cell function
… to study exocytosis measured as changes in cell membrane capacitance. In beta cells, biphasic exocytotic pattern was previously mainly attributed to insulin granule pool depletion. In paper I, we used the pulse length protocol and mixed-effect modelling; the latter takes care of cellular …
-
An electrical microcytometer for portable blood analysis in global health applications
… of leukocytes, such as cell volume and membrane capacitance. Different electrical sensor designs were investigated to increase sensitivity and signal integrity, and to know cell flow direction through the counter. Various sensing channel designs were explored to determine the optimal …