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Showing 1 to 20 of 146 for “"malformations"”.

  1. Anorectal malformations - their impact on early phases in life

    Abstract: Background : Anorecta l malformation s (ARM) occur in 4: 10000 newborn children with the gender distribut ion 1:1.5 females:males. The reconstruction of ARM, posterior sagiccal anorectal plasty (PSARP), was implemenred worldwide in the late 1980s and therefore the follow-ups are limited. …

    lund Repository record for Anorectal malformations - their impact on early phases in life (opens in a new tab)

  2. Investigation of the Molecular Mechanism for Cerebral Cavernous Malformations

    <p>Cerebral cavernous malformations (CCM) are vascular anomalies of the central nervous system comprised of grossly-dilated blood-filled capillaries. CCM leisons may occur sporadically or by inheritance of a mutation in one of three genes, <italic>CCM1</italic>, <italic>CCM2</italic>, or …

    duke Repository record for Investigation of the Molecular Mechanism for Cerebral Cavernous Malformations (opens in a new tab)

  3. Developmental Malformations in Zebrafish Caused by Exposure to Environmental Pollutants

    … environmental chemicals causing congenital malformations. High-throughput screening of 292 unique chemicals from the ToxCast Phase I library identified 38 skeletal disruptor compounds (SDCs) producing bone and craniofacial cartilage malformations in zebrafish. We used ToxCast in vitro data …

    houston Repository record for Developmental Malformations in Zebrafish Caused by Exposure to Environmental Pollutants (opens in a new tab)

  4. Notch deficiency leads to arteriovenous malformations and altered pericyte function

    … mice display retinal arteriovenous malformations (AVM) characterized by dilated vessels, vascular tangles and arteriovenous shunts that are similar to human brain AVMs. Disruption of pericyte/endothelial cell association is accompanied by an increase in vascular density, venule …

    columbia-diss Repository record for Notch deficiency leads to arteriovenous malformations and altered pericyte function (opens in a new tab)

  5. Birth prevalence of ano-rectal malformations for the Western Cape Province, South Africa

    Background: Anorectal malformations (ARMs) are a major birth anomaly worldwide. South Africa has ethnically and geologically diverse populations. A recent publication indicated an increased birth prevalence of ARMs in the Witwatersrand referral area between 2005 and 2010. The purpose of this study …

    cape-town Repository record for Birth prevalence of ano-rectal malformations for the Western Cape Province, South Africa (opens in a new tab)

  6. KLF4 IS A KEY DETERMINANT IN THE DEVELOPMENT AND PROGRESSION OF CEREBRAL CAVERNOUS MALFORMATIONS

    Cerebral cavernous malformations (CCMs) are capillary-venous malformations located in the central nervous system that often lead to neurological deficits and cerebral hemorrhage. Pharmacological treatment limiting disease progression is dearly needed, as available therapy is limited to surgical …

    milano Repository record for KLF4 IS A KEY DETERMINANT IN THE DEVELOPMENT AND PROGRESSION OF CEREBRAL CAVERNOUS MALFORMATIONS (opens in a new tab)

  7. Complex thoracic malformations: is there an association between adolescent idiopathic scoliosis and pectus excavatum?

    … (AIS).Objectives: When combined thoracic malformations occur scoliosis and pectus excavatum (PE) may limit the space available in the mediastinum resulting in cardiopulmonary compromise. The purpose of this study was to evaluate the prevalence of radiographic PE in patients with AIS. …

    umn Repository record for Complex thoracic malformations: is there an association between adolescent idiopathic scoliosis and pectus excavatum? (opens in a new tab)

  8. Uniparental disomy as a cause for congenital malformations and or developmental delay in inherited apparently balanced chromosomal rearrangements

    … disomy may cause mental retardation and malformations in carriers of an inherited apparently balanced chromosomal translocation. We studied 7 families in which one or more childen with congenital anomalies and mental retardation have inherited an apparently balanced translocation from a …

    ubc Repository record for Uniparental disomy as a cause for congenital malformations and or developmental delay in inherited apparently balanced chromosomal rearrangements (opens in a new tab)

  9. Anorectal Malformations at Children's Health: Understanding Our Patient Population, Patterns of Disease, and Surgical Outcomes Over a 10-Year Period

    PROBLEM: Children with anorectal malformations require complex procedures and often require long-term bowel management and clinical care for optimal quality of life. The demographics and outcomes of patients with anorectal malformations at Children's Health are unknown. METHODS: The electronic …

    utswmed Repository record for Anorectal Malformations at Children's Health: Understanding Our Patient Population, Patterns of Disease, and Surgical Outcomes Over a 10-Year Period (opens in a new tab)

  10. Das Wissen in der Bevölkerung über angeborene Fehlbildungen und Down-Syndrom unter Berücksichtigung demographischer und biographischer Faktoren

    … of knowledge in the population about congenital malformations and Down’s syndrome under consideration of demographic and biographic features of the respondents.The data of the 2005 evaluated questionnaires (return quota: 66.8%) were examined with uni- and multivariate methods of …

    aachen Repository record for Das Wissen in der Bevölkerung über angeborene Fehlbildungen und Down-Syndrom unter Berücksichtigung demographischer und biographischer Faktoren (opens in a new tab)

  11. Veränderung der gesundheitsbezogenen Lebensqualität vor und nach interventioneller radiologischer Therapie bei Patienten mit angeborenen Gefäßmalformationen

    … quality of life in patients with vascular malformations before and after a interventional radiological therapy was examined. It had to be clarified, how the health-referred quality of life and/or which dimensions of the quality of life changes after a interventional radiological therapy in …

    aachen Repository record for Veränderung der gesundheitsbezogenen Lebensqualität vor und nach interventioneller radiologischer Therapie bei Patienten mit angeborenen Gefäßmalformationen (opens in a new tab)

  12. A novel low-density lipoprotein receptor-related protein protects against environmental teratogens

    Congenital malformations are the leading cause of infant mortality in the United States, and 2% of all live births have some form of malformation. While many of these malformations have known genetic or environmental causes, others have eluded explanation. These conditions are thought to be caused …

    texas Repository record for A novel low-density lipoprotein receptor-related protein protects against environmental teratogens (opens in a new tab)

  13. G-Protein-Coupled Estrogen Receptor-1 (GPER): A Potential Target For Xenoestrogens During Vertebrate Embryogenesis.

    … antagonist (G-15) - resulted in developmental malformations; and (3) co-exposure with G-15 blocked G-1-induced teratogenesis, suggesting that G-1 toxicity is mediated via aberrant GPER activation. Based on these data, we hypothesized that the developing cardiovascular system was the primary …

    south-carolina Repository record for G-Protein-Coupled Estrogen Receptor-1 (GPER): A Potential Target For Xenoestrogens During Vertebrate Embryogenesis. (opens in a new tab)

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