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Showing 1 to 2 of 2 for “"licofelone"”.
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Changes In The Testes Following Spinal Cord Injury and The Attenuating Effects of Licofelone
… many of these changes with early treatment with licofelone, a dual cox/lox inhibitor, including attenuation of bile acid levels, lysolipids, inflammation, and oxidative stress. This indicates a promising avenue for future research into alleviating this symptom of a devastating injury.</p>
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Novel Use of Dual Anti-Inflammatory Therapy to Overcome Drug Resistance and Improve Functional Recovery Following Spinal Cord Injury
… the ability of the dual COX-/5-LOX inhibitor licofelone to attenuate Pgp-mediated drug resistance following SCI. Licofelone treatment both reduced spinal cord Pgp levels and enhanced spinal cord riluzole bioavailability following SCI. Thus, we propose that licofelone may offer a new …