Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 51 for “"kidney failure"”.
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Drop-out of children with end stage kidney failure from chronic Peritoneal dialysis and associated factors; a ten year review at Red Cross War Memorial Children's Hospital (RCWMCH), Cape Town, South Africa
… the child healthy and alive when in end stage kidney failure (ESKF) while being worked up for kidney transplant, the preferred treatment. Chronic peritoneal dialysis (PD) is the preferred first choice of dialysis modality in many centers because of its advantages over hemodialysis (HD). In …
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Studying glomerular disease epidemiology: tackling challenges and paving a path forward
… diseases are a group of rare immune-mediated kidney diseases that affect the glomeruli, or filtering units, of the kidney. Major knowledge gaps remain in our understanding of glomerular disease epidemiology. Efforts to describe glomerular disease distributions based on geographic, demographic, …
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Care and Outcomes for Older Adults with Advanced Chronic Kidney Disease
… prevalence of older adults with advanced chronic kidney disease (CKD) is increasing globally, although optimal treatment remains uncertain. We examined in this thesis survival outcomes for older adults with kidney failure treated and not treated with dialysis. We also sought to identify barriers …
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The structure of testis angiotensin-converting enzyme (tACE-g13) in complex with the inhibitor RXPA380
… of myocardial infarction, hypertension, kidney failure and heart failure.
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Sex and Gender Differences in Patient Outcomes in Individuals Living with Chronic Kidney Disease
More than 48,000 Canadians live with kidney failure and require life-sustaining kidney replacement therapy, in the form of dialysis. The prevalence of dialysis continues to rise, increasing by 1.6% annually, with the majority of patients initiating in-centre hemodialysis (ICHD) compared to …
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Estudio de prefactibilidad para la instalación de un centro de hemodiálisis
Currently, kidney failure is a disease that occurs when the kidneys suddenly lose the ability to filter waste from the blood. When this occurs, harmful levels of waste can accumulate and there may be an imbalance in the chemical composition of the blood. There are two types of renal failure: acute …
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The prevalence and severity of the symptom burden in patients with End Stage Renal Disease (ESRD) in a resource limited setting
Globally, kidney failure is Increasing. In South Africa, limited access to kidney replacement therapy (KRT) necessitates urgent improvement in kidney supportive and palliative care. Methods: This prospective, cross-sectional, mixed-method study was conducted at two Cape Town hospitals from June …
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Please Be Patient : A Cultural Phenomenological Study of Haemodialysis and Kidney Transplantation Care
… examines the practice of haemodialysis and kidney transplantation, the two medical therapies available for persons with kidney failure, from a phenomenological perspective. A basic assumption made in the thesis is that contemporary biomedicine is deeply embedded in the cultural, historical, …
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The structural and functional characterisation of the PLAT domain of polycystin-1
Autosomal dominant polycystic kidney disease (ADPKD) is one of the commonest monogenic disorders of man, affecting approximately 1 in 1000 of the world’s population. It is characterised by the progressive development and expansion of renal cysts, which eventually replace the normal architecture of …
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Reclaiming the Docile Body: An Autoethnography of Illness and Adult Education.
… education context. I first became ill with acute kidney failure in January 2011, a few months after giving birth to my son. It happened so suddenly and unexpectedly. I was thrown into a completely different world, questioning and reflecting on my life up to that point. In this thesis, I will show …
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On-patient medical information encoding : image guided fistula cannulation assistant for hemodialysis
… dialysis treatment for patients afflicted with kidney failure. Implemented as a temporary tattoo, the medical system is intended to be widely deployable in a variety of settings for a myriad of populations, including developed and emerging medical communities, in-clinic or at-home, and across a …
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Cultural Competency in Healthcare Policy: Pursuing Elder, African-American Diabetics as Stakeholders in Successful Treatment
… of diagnosis, higher limb amputation, increased kidney failure, and stroke. While the disparities have been documented, elder, African-American diabetics rarely have been invited into discussions concerning these disparities, research questions, project or program design, and results. They are …
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The role of diet therapy in chronic kidney disease
Background Chronic kidney disease (CKD) is a condition characterized by gradual loss of kidney function over time. Millions of adults have CKD and those who have diabetes, hypertension, and family history of kidney failure are at highest risk of its development. Patients may develop comorbidities, …
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Effects of inulin supplementation on markers of mineral and bone metabolism and the gut microbiota in hemodialysis patients
Up to 80% of patients with chronic kidney disease (CKD) have some degree of mineral and bone disorder (MBD), which is associated with higher morbidity and mortality, specifically from cardiovascular causes. Despite the pharmacological treatment for MBD, its prevalence remains high, especially for …
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A descriptive survey of renal unit practitioners' knowledge, attitude and practice relative to use and effects of unfractionated heparin in selected adult chronic haemodialysis centres in the Cape Town metropole
… adult patients diagnosed with stage 5 end-stage kidney failure. During the procedure 200-250 ml/minute of the patient's blood volume is extracorporeal and patency of the circuit is maintained by an anticoagulant, for example, unfractionated heparin (UFH). Incorrect dosage or time of …
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Are gadolinium contrast media really less nephrotoxic than iodine agents in radiographic examinations? A comparison in relation to their ability to attenuate x-rays in a pig model
… post-injection. III) After the experiments the kidneys were evaluated histomorphologically. Results: I) In vitro measurements indicate that 0.5M Gd-CM are equal attenuating with 60-80 mg I/mL at commonly used 70-90 kVp for XRA and with 110 mg I/mL at 120 kVp CT using a body phantom. II) …
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Using human induced pluripotent stem cells to model cystinosis
… lysosomes in most cells of the body, however the kidney is the main organ affected. For poorly understood reasons, renal proximal tubule (PT) cells lose their functionality and degenerate in cystinosis, forming a characteristic “swanneck” lesion that leads to kidney failure before 10 years of age. …
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STUDIES ON ANGIOTENSIN-(1-7) AND MITOCHONDRIA: THE ROLE OF AN INTRACELLULAR RENIN-ANGIOTENSIN SYSTEM WITHIN THE KIDNEY
… to treat high blood pressure and the resulting kidney failure target a classic circulating hormonal system - the renin-angiotensin System (RAS), and specifically, the ACE-Ang II-AT1 receptor axis. We have focused strategically on investigating novel intracellular pathways by which Ang-(1-7) is …
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Separation-individuation and its effect on diabetes management and diabetes control in young women with Type 1 diabetes
… at increased risk of heart disease, stroke, kidney failure, blindness, and amputation. The incidence of Type 1 Diabetes has increased in countries world wide including Australia. During adolescence and young adulthood diabetes management and control have been found to deteriorate placing the …
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A Novel Role For Dyrk1A In Kidney Development
<p>Congenital anomalies of the kidney and urinary tract (CAKUT) are a leading cause of pediatric kidney failure and encompass a wide range of structural malformations resulting from defects in morphogenesis. CAKUT occur in ∼1/500 live births and with an average wait time of 3-5 years for a kidney …
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