Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"ion permeability"”.
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Effect of shear stress on surface membrane potassium ion permeability of calf pulmonary artery endothelial cells (Potassium ion)
… of shear stress on membrane potassium (K$\sp+$) permeability in vascular endothelial cells. Cultured monolayers of calf pulmonary artery endothelial cells, preloaded with $\rm \sp{86}Rb\sp+$, were subjected to different levels of fluid shear stress in the range 1-10 dynes/cm$\sp2$, in a …
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Cell-Cycle Specific Biosynthesis of the Photosynthetic Membrane of Rhodopseudomonas Sphaeroides: Structural Implications
Fusion of chromatophores, the photosynthetic membrane vesicle isolated from the intracytoplasmic membranes (ICM) of the photosynthetic bacterium Rhodopseudomonas sphaeroides, was achieved by the use of polyethylene glycol as fusogen. Ultracentrifugation, electron microscopy (EM), intrinsic density …
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Viscoelastic two-dimensional modeling of cell deformation due to shear stress on apical focal adhesion, with experimental design considerations
Introduction: Cells are exposed to a wide variety of forces within the human body, and the mechanisms by which cells respond to these forces are largely unknown. From altering gene transcription in the cell nucleus to conformational changes in membrane channel proteins that lead to increased or …
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Evaluations of concrete overlays for bridge deck applications
… service life, but in several cases delamination and failures have been observed. A comprehensive study has been recently defined to investigate overlays performance and delamination, culminating eventually in the development of specifications in collaboration with WVDOH and the Contractors …
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Quantification of membrane transport rates using optofluidics
The transport of ions and small molecules across membranes is a ubiquitous process in biological systems. Effective studies of membrane transport phenomena require suitable model membrane systems, efficient methods to quantify transport kinetics and a robust theoretical framework to derive …
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Structural Elucidation of the Interaction Between Neurodegenerative Disease-Related Tau Protein with Model Lipid Membranes
… That folded structure is linked to protein function, and misfolding to dysfunction. Protein misfolding and aggregation into β-sheet rich fibrillar aggregates is connected with over 20 neurodegenerative diseases, including Alzheimer's disease (AD). AD is characterized in part by misfolding, …
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Computational Insights into the Antimicrobial Mechanism of Action of Class II Bacteriocins.
… detailed understanding of their mechanism of action is required. This mechanistic insight will offer ways to control and optimize their activity and selectivity against specific pathogens, greatly enhancing their potential for medical applications. The goal of this work is to elucidate the …
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Development and evaluation of a fluorescence emission ratio-based fiber opticpH measurement system for use in monitoring changes in tumor pH during clinical hyperthermia
… during such therapy due to the inherent limitations of the microelectrode technique in the presence of a microwave field. A fiber optic pH measurement system, due to its dielectric nature, provides a method for overcoming such limitations. Optrodes sensitive to pH have been studied based on …
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Structural and functional role of the extracellular loops and C-terminal domain of the voltage-gated sodium ion channel
Voltage-gated sodium ion channels (Nav) are central to action potential initiation through regulating the entry of sodium ions (Na+) into excitable cells including cardiomyocytes and neurones. The α-subunit of Nav consists of four homologous domains (DI-DIV), each consisting of six transmembrane …
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A Computational Study of The Electrical Response of Biological Cells with Realistic Three-Dimensional Morphologies
… extracellular matrix and governs the distribution of the cytoskeleton to control the three-dimensional (3D) morphology of a cell. From an electrical standpoint, the cell membrane represents an insulating layer with selective ion permeability, thereby administering an ionic imbalance between the …
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A Study of Ionic Permeability Changes Underlying Excitation in Myelinated Nerve Fibers of the Frog
<p>Investigations by Huxley and Stämpfli of the dependence of the resting potential and of the action potential at the node of Ranvier upon the ionic composition of the bathing medium provided evidence that the electrical activity resulted from a sequential alteration of the membrane permeability …
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The Role of Time Variant Resistance and Electromotive Force in Ionic Systems Related to Cell Membranes: The Excitability Properties of Frog Skin and Toad Bladder
… of the electrical properties of cells is the permeability of the plasma membrane to the ions passing across this structure; it has been our purpose to explore, both theoretically and experimentally, the physical implications of this point-of-view. The cornerstone of our analysis has been the …
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A Pharmacological Analysis of the Ionic Channels of Nerve
… currents selectively, and tetraethylammonium ion abolished the potassium currents selectively. Neither of these drugs affected the time constants associated with any of the current components. The curves relating the kinetic parameters of the sodium currents to the voltage were displaced along …
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Mineralogical and ion-exchange leaching study of a Rare Earth Element (REE) bearing ion-adsorption clay deposit
… total REE output. This has prompted the evaluation of ion-adsorption clay (IAC) deposits in tropical regions outside China, namely Madagascar. Clay minerals such as kaolinite are part of the phyllosilicate class, containing structures of shared octahedral aluminium and tetrahedral silicon …