Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 22 for “"genetic inheritance"”.
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An investigation into the understanding of basic genetic inheritance amongst amaXhosa caregivers of patients with Haemophilia
… to explore the level of understanding of basic genetic inheritance among isiXhosa-speaking caregivers of patients with the genetic bleeding disorder haemophilia. Haemophilia A and B are X-linked recessive inherited, lifelong bleeding disorders that are caused by deficiencies in blood clotting …
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Exploring the impact of polygenes on genetic inheritance model identification, with application to Familial Colorectal Cancer Type X (FCCTX)
Although a genetic inheritance pattern has not yet been identified, there seems to be a hereditary component for some types of cancer. The focus of this thesis is on identifying the factors that enable correct identification of genetic inheritance models. Exploring this topic involved complex …
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Response of Soybean Iron and Manganese Deficiency
… yield losses associated with these deficiencies, genetic resistance is more reliable and effective. Identification of resistant cultivars requires an understanding of the genetic inheritance for resistance, knowledge of the physiological mechanisms involved with resistance, and the development of …
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The Illuminated Empty Spaces
… collection that focuses on themes of grief, inheritance, memory, and sexuality. Genetic inheritance, inherited trauma, and the tangible inheritance of physical objects are all explored throughout the work. The project was inspired by the loss of my mother, and my subsequent diagnosis with a …
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Effect of Gender on the Association of Single-Nucleotide Polymorphisms with Bipolar Disorder
… form of mental illness that depends strongly on genetic inheritance for expression. The author of this study has sought to evaluate whether the gender of subjects influences which genetic variants are associated with the disease. A portion of the cases from a previously published study were …
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Problems in Pedigrees and Phylogenies
The footprint of genetic inheritance can be observed among both familial relationships between individuals and evolutionary relationships between species. The former can be depicted by a pedigree, whereas the latter can be depicted by a phylogeny. These two distinct objects can be viewed as …
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Friction Ridge Dysplasia and Its Preponderance in the Afghanistan Population
<p>Friction Ridge Dysplasia is a rare genetic disorder in which the friction skin ridge units do not fuse together to form continuously flowing friction ridges. The skin affected by Friction Ridge Dysplasia is generally localized to one area and gives a similar appearance of the pebbled state of …
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Molecular genetic investigations of renal cell carcinoma predisposition
… (RCC) are a diverse group of histologically and genetically distinct renal neoplasms accounting for 2.4% of all cancers worldwide. While a majority of RCC cases are sporadic in nature, a proportion are due to genetic predisposition caused by syndromic and non-syndromic conditions. Inherited renal …
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Intergenerational and Transgenerational Effects of Endocrine Insults
Environmental perturbation can lead to non-genetic, non-Mendelian transmission of acquired traits to descendants. Such inheritance may be intergenerational or transgenerational, the latter describing effects that persist in the absence of any exposure (either directly or of parental germ cells) to …
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On the Functions of Morality
… of evolutionary processes. Humans have a dual inheritance system involving both cultural and genetic inheritance that makes analysis of function for them particularly complex. In this dissertation, I develop a set of conceptual tools for those who wish to naturalize. I begin by developing an …
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Inheritance of resistance to selected pyrethroid insecticides in <i>Blattella germanica</i> (Dictyoptera: Blattellidae)
… and phenothrin were employed to study the inheritance of resistance to pyrethroid insecticides in the Seasons strain of <i>Blattella germanica</i>. This resistance was found to be an autosomal, probably monofactorial character, not linked with the black body or orange body mutants that …
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RELATIONSHIPS BETWEEN INTERNALIZED STEREOTYPES, BLACK IDENTITY, RACE SALIENCE, AND SELF-ESTEEM AMONG AFRICAN AMERICAN COLLEGE STUDENTS
… to the first research hypothesis, stereotypes of genetic inheritance (SGI) were endorsed by more students at HBCUs than at HWCUs. As hypothesized, degree of Black Identity as defined by private regard was negatively related to stereotypes of mental ability (SMA). Supplemental findings were also …
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Maternal Adverse Childhood Experiences and Infant DNA Methylation: Examining an Epigenetic Biomarker of Intergenerational Risk
… as opposing influences on human development, epigenetics is one area of study investigating how these influences work together. Until recently, transmission of intergenerational risk to human development has centred on claims of genetic inheritance, or the persistence of poor social environments …
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Treslin and its role in the assembly of the replicative DNA helicase
… an essential biochemical process that underlies genetic inheritance. In eukaryotic cells, this process is carried out by a multi-subunit protein complex called replisome. The core of replisome is made up of six-subunit protein ring Mcm2–7, which contains weak DNA helicase activity. In order to …
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Hereditary risk factors for stroke in humans - Association studies with emphasis on familial and genotypic factors
… The aim of this thesis was to assess possible genetic impact on stroke risk. We thus evaluated family history of stroke-related individual traits as well as allelic variations in selected candidate genes. Methods Association studies, primarily of Lund Stroke Register data, were fundamentals in …
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Rehearsal for survivorship: a qualitative analysis of later life husbands and wives
… factors highlighted were the sense of one's genetic inheritance, belief in the “common wisdom" that husbands pre-decease their wives, and observations of one's own energy level relative to one's partner. The second part of the study explores the worries and concerns of men and women as they …
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Phytophthora nicotianae: Fungicide Sensitivity, Fitness, and Molecular Markers
… preventively; i.e. before infections occur. The genetic inheritance of mefenoxam resistance in P. nicotianae was studied using F1 progenies of a cross between resistant and sensitive isolates. The F1 progenies segregated for mefenoxam resistance in ratio of 1R:1S, indicating the mefenoxam …
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Responses to transposon activity and genome damage during germline development
… is the cell lineage that is responsible for the inheritance of genetic information in multicellular eukaryotes. In most animal species, germ cells are set aside from somatic lineages during early embryonic development and follow a unique developmental programme that culminates in the production …
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From the simple to the complex: an examination of different herbicide resistances
… purpose of this thesis was to determine the genetics and inheritance of both target-site- and non-target-based resistances to provide beneficial insights into resistance evolution, adaptation dynamics and management practices. Chapter 2 discusses research conducted to determine if a Tennessee …
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Social Evolution in Action: Causes and Consequences
… focussing more on the specific mechanisms of inheritance and how social behaviours of one partner induce the evolution of traits in others. The aim of this thesis is to unite these approaches by asking how adaptive social behaviour (i.e. parental care) can potentially influence evolution: by …
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