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Showing 1 to 20 of 28 for “"furosemide"”.
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Investigation of Enhancement of Furosemide Solubilization with Cyclodextrins and a Novel Octenyl Succinate Anhydride Starch
… <p>Chapter 4 explores a solid dispersion of furosemide and sulfobutylether-β-cyclodextrin which was another derivative excipient of starch. Solid dispersion preparation method and mechanism are also discussed. The work serves as a positive control for OSA starch solid dispersion. Comparison …
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Development of paediatric dosage forms of furosemide using the problem structuring method of morphological analysis
… to decide which pharmaceutical dosage forms of furosemide would be selected as a solution space for paediatric patients with low cardiac output syndrome. Morphological Analysis application resulted in the selection of two different dosage forms for further work (Microemulsion oral liquid dosage …
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The effects of furosemide on equine skeletal muscle satellite cell myogenesis and metabolism in vitro
… result in fatality. Presently, the loop diuretic furosemide is the only medication approved to mitigate the effects of EIPH. Often regarded in the racing industry as "performance enhancing" due to 4% weight loss ensued by its diuretic effect, it is unknown what effects furosemide may have on …
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Effects of Furosemide and Oleic Acid On Thyroxine Binding to Isolated Pairs of Thyroxine Binding Serum Proteins
… TBG-TTR, TBG-albumin and TTR-albumin, by furosemide (0.0 to 1.0 mol/L) and oleic acid (0.0 to 0.10 mol/L) were studied using equilibrium dialysis with purified binding proteins at concentrations 1/200 of levels in normal human sera, separated across the dialysis membrane and competing for …
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Effects of Low and High Sodium Chloride Diets and Furosemide Administration on Cardiac Function, Plasma Electrolyte Concentrations, and the Renin-Angiotensin-Aldosterone System
… was to assess the roles of dietary sodium and furosemide on cardiac function, plasma electrolyte concentrations, and the renin-angiotensin-aldosterone system, in healthy canines. Twenty mixed-breed canines were allotted to one of four groups, Group I - Dogs fed low sodium diet (0.08% sodium), …
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The efficacy of short term amoxicillin therapy and the effect of furosemide on conventional antibiotic therapy in experimentally induced bacterial lower urinary tract infection in cats
… controls. During the study period the diuretic furosemide was used in some cats to facilitate cystocentesis procedures. Those cats were observed to exhibit less stranguria, which is a common sign of lower UTI. The second study evolved from observations made in the first study and evaluated the …
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Mechanisms and Management of Breathlessness in Chronic Heart Failure
… It focuses on the potential of nebulised furosemide as an adjunct treatment, given its excellent safety record and existing evidence that it modulates dyspnoea via direct action on lungs. Methods: A multi-dimensional questionnaire was used to survey the prevalence of dyspnoea in the heart …
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Renal Blood Oxygen Level Dependent (BOLD) Magnetic Resonance Imaging with an Acute Furosemide Stimulus as a Tool to Evaluate Kidney Physiology in Patients Suspected of Renal Artery Stenosis
… evaluate the acute effects of the loop diuretic furosemide on kidney physiology using novel magnetic resonance imaging techniques. Blood Oxygen Level Dependent (BOLD) magnetic resonance imaging has recently been utilized as a noninvasive tool to detect kidney oxygenation in a number of renal …
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Metolazone in Diuretic Refractory Ascites
… mg of metolazone and Group 2 received 80 mg of furosemide. Both groups received their basal diuretic regimen. 24 hour urinary sodium was measured to compare the two groups. Results: Metolazone group increased their 24 hr sodium excretion by 127±150.4 meq as compared to 44.5± 32.6 meq in the …
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EXISTÊNCIA DA ALÇA DE HENLE EM CHELONOIDES DENTICULATUS E EFEITOS DA FUROSEMIDA EM CHELONOIDES DENTICULATUS (Linnaeus, 1766) E CHELONOIDES CARBONARIUS (Spix, 1824)
… besides, to test the action of the diuretic furosemide in the jabutis Chelonoides denticulatus and Chelonoides carbonarius, since the presence of this structure generates Subsidies for the use of drugs that act on it. For histology, renal fragments of C.denticulatus were collected and …
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Effect of Compression Force on Agglomeration of Micronized Active Pharmaceutical Ingredients: Techniques to Prevent API Agglomeration During Compression
… dissolution rate of the API.</p> <p>Micronized furosemide and griseofulvin were used as model API’s based on the biopharmaceutical classification system to study the effect of compression force on particle agglomeration during compression and also to study the processes and materials to prevent …
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ΕΠΙΔΡΑΣΗ ΔΙΟΥΡΗΤΙΚΩΝ ΦΑΡΜΑΚΩΝ ΣΤΗ ΝΕΦΡΙΚΗ ΑΠΕΚΚΡΙΣΗ ΤΟΥ ΨΕΥΔΑΡΓΥΡΟΥ
… RENAL ZINC EXCRETION WAS STUDIED BY: A) INFUSING FUROSEMIDE INTRAVENOUSLY (20 MG), ALONE OR IN COMBINATION WITH SODIUM LOADING (INFUSION OF 2 LT ISOTONIC SALINE 24 H BEFORE AND CONCOMITANT INFUSION OF 250 ML ISOTONIC SALINE DURING THE ADMINISTRATION OF FUROSEMIDE) IN 11 HEALTHY VOLUNTEERS AND B) …
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Medications, sex hormones and reproductive factors in relation to gastro-oesophageal cancer risk and survival
… vitro experiments have shown furosemide inhibited gastro-oesophageal cancer cell proliferation. However, the association between furosemide use and gastro- oesophageal cancer survival in humans has not been studied. A cohort study using UK primary care records from the Clinical …
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Preparation of amorphous forms to increase the solubility of poorly soluble drugs using spray drying
… using three model drugs-naproxen, ketoprofen and furosemide. Physical mixtures of the model drug with polyvinylpyrrolidine and spray dried composites were subjected to Fourier Transform Infrared Sprectroscopy (FTIR), Differential Scanning Calorimetry (DSC) and Powder X-ray Diffraction (XRPD). The …
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ΕΠΙΔΡΑΣΗ ΤΗΣ ΔΙΑΤΟΜΗΣ ΤΟΥ ΟΠΤΙΚΟΥ ΝΕΥΡΟΥ ΕΠΙ ΤΗΣ ΕΝΔΟΦΘΑΛΜΙΟΥ ΠΙΕΣΕΩΣ ΚΑΙ ΔΡΑΣΕΩΣ ΩΣΜΩΤΙΚΩΝ ΚΑΙ ΜΗ ΔΙΟΥΡΗΤΙΚΩΝ ΣΕ ΑΥΤΗΝ
… MANNITOL AND ASCORBIC ACID), ACETAZOLAMIDE, FUROSEMIDE, NACL O,9% AND WATER LOADING TEST WERE STUDIED IN EITHER EYES WITH INTACT OR TRANSECTED OPTIC NERVE. FINALLY THE EFFECT OF THE ABOVE MENTIONED SUBSTANCES ON THE WEIGHT OF VITREOUS, AQUEOUS AND LENS WAS DETERMINED IN BOTH EYES. THE I.O.P. …
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Purine transport in plasmodium falciparum
… through the hFNT1 was unexpectedly inhibited by furosemide. This inhibition by furosemide of [3H]-hypoxanthine and [3H]-adenine uptake was not through inhibition of the NPP, as it was observed equally in infected and uninfected hRBC. To gain further understanding of purine transport in the …
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Modulation Of Renin Secretion By Renal Cortical Interstitial Calcium
… ascending limb sodium chloride reabsorption with Furosemide increased PRA without effecting major changes in renal cortical interstitial calcium. Our data support the notion that hypercalcemia inhibits PRA via PTH-mediated increases in renal cortical interstitial Ca that act on the CaSR.</p>
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Influence of Carbon Dioxide on Electrophysiology and Ionic Permeability of the Basolateral Membrane of Frog Skin (Epithelia, Ionic Flux, Cellular Ph)
… Cl('-) transport appeared to be electroneutral, furosemide and SITS sensitive, and for the most part at least not coupled to the fluxes of Na('+) and K('+). Although CO(,2) caused a partial inhibition of pump activity as assessed from decreases of pump-mediated Na('+) efflux and K('+) influx, …
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Salsalate Inhibition of Thyroid Hormone Transport : A Model of the Euthyroid Sick Syndrome
… inhibitory effects of salsalate, salicylate and furosemide using the inhibitor assay.</p> <p>The thyroid hormone changes following a single oral dose of salsalate exhibited the major characteristics of the euthyroid sick syndrome, which are the inhibition of T<sub>4</sub>binding to serum …
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Characterization of a human renal organic anion transporter
… and the loop diuretics bumetanide and furosemide. Uptake also showed chloride dependence, characteristic of the basolateral organic anion/dicarboxylate exchange in renal systems. Mutation of two amino acids, Lys382 and Arg466, positions positively charged in all OATs and negatively …
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