Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 113 for “"frontal cortex"”.
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Electrophysiological characterization of the dorsomedial frontal cortex of the rhesus monkey
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Brain and Cognitive Sciences, 1992.
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Assessing Pre-Frontal Cortex Oxygenation After Sport Concussion With Near Infrared Spectroscopy
… spectroscopy (NIRS) was used to assess pre-frontal cortex oxygenation, by measuring relative changes in oxy- (HbO2 ) and deoxy-hemoglobin (HHb), and the associated standard deviations. Resting hemoglobin, and hemoglobin changes in response to increases in CO2 (induced by 20s breath-holds), …
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AN ANATOMICAL AND IMMUNOCYTOCHEMICAL STUDY OF THE PRIMATE TEMPORAL AND FRONTAL CORTEX
… carried out on the human and monkey temporal cortex, and, for comparison, the human frontal cortex. The neurons were studied by light and electron microscopy, and some of their immunocytochemical characteristics elucidated. Neurons in much of the left temporal cortex, apart from area 41, …
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Eye and arm movement-related activity in dorsomedial frontal cortex of monkey
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Brain and Cognitive Sciences, 1999.
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HD-tDCS over Frontal Cortex and Neuropsychological Functioning in Cognitively Impaired Older Adults
… at altering neuronal activity in the brain. The frontal cortex serves as a brain circuitry hub connected to a variety of cortical and subcortical structures. Within the frontal cortex lies the dorsal anterior cingulate cortex (dACC) and pre-supplementary motor area (preSMA), which are …
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Beta oscillations in frontal cortex and striatum represent post-processing of successful behavior
Beta band (13-30 Hz) oscillations in sensorimotor cortex are associated with motor performance, but the nature of this relationship is not clear. Recently, excessive beta activity in cortico-basal ganglia circuits has been recognized as a hallmark of Parkinson's disease. Renewed interest in beta …
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Effects of frontal cortex and caudate nucleus lesions on stimulus generalization learning in rats
… consequences in rats of lesions of the frontal pole area (FP), the anterior median cortex (AM) described by Leonard, and the caudate nucleus (CN) on a brightness stimulus generalization task. It was hypothesized that deficits in stimulus generalization learning would be demonstrated by …
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The role of frontal cortex in the generation of saccadic eye movements and fixation
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Brain and Cognitive Sciences, 1995.
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Concentration-dependent Effects of D-Methylphenidate on Frontal Cortex and Spinal Cord Networks in vitro
Spontaneously active frontal cortex and spinal cord networks grown on microelectrode arrays were used to study effects of D-methylphenidate. These central nervous system tissues have relatively low concentrations of dopaminergic and noradrenergic neurons compared to the richly populated loci, yet …
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Molecular and Functional Characterization of Pyramidal Cell Types in the Frontal Cortex of Mouse Brain
<p>Mammalian neocortex is the most complex structure in the brain. Considered the seat of executive function, the neocortex subserves diverse cognitive processes such as decision-making, motor planning, sensory discrimination and memory consolidation. The cellular heterogeneity of the neocortex …
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The involvement of the primate frontal cortex-basal ganglia system in arbitrary visuomotor association learning
It is the goal of this thesis to examine the frontal cortex-basal ganglia system during arbitrary visuomotor association learning, the forming of arbitrary links between visual stimuli and motor responses (e.g. red means stop), a fundamental learning process that underlies much of our complex …
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Mouse cortical cholinergic neurons: Ontogeny of phenotypes in vivo and in vitro.
The development of cholinergic neurons in mouse frontal cortex was studied both in vivo and in vitro by immunocytochemistry with an antibody to choline acetyltransferase (ChAT), the enzyme responsible for acetylcholine synthesis. While cortical cholinergic neurons have previously been characterized …
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The Effect of Organophosphate Exposure on Neocortical, Hippocampal and Striatal Monoamines: A Potential Substrate for Chronic Psychiatric, Cognitive and Motor Dysfunction
… oil vehicle. Brains were rapidly removed and the frontal cortex, hippocampus and striatum were bilaterally dissected on ice. These three regions from one side were assayed for AChE activity, while those from the opposite side were processed for high performance liquid chromatography with …
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The Role of β-synuclein in the Pathological Mechanisms of Dementia with Lewy Bodies
… levels of α-synuclein and β-synuclein in the frontal cortex, occipital cortex and hippocampus of patients with DLB and age-matched controls was performed. Evidence is provided here for a neuronal increase of β-synuclein within the frontal cortex and a decrease in occipital cortex of DLB …
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Persistent “hijacking” of brain proteasomes in HIV-associated dementia
… Tissue Consortium, including clinical data and frontal cortex brain tissue from 153 autopsy cases. Assessment of frontal cortex proteasome proteolytic activity revealed an abnormal catalytic profile that was more severe in those with HIV-associated neuropsychological impairment or HIV …
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Behavioural disinhibition in the syndromes associated with frontotemporal lobar degeneration
… was used to measure glutamate and GABA in the frontal cortex of 44 patients with a FTLD syndrome and 20 healthy controls. Bayesian modelling of a response inhibition task was used to quantify behavioural disinhibition. Both neurotransmitters were reduced in the frontal cortex, but not occipital …
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Low-Input Multi-Omic Studies of Brain Neuroscience Involved in Mental Diseases
… using NeuN+ neuronal nuclei from the mouse frontal cortex after a single dose of psychedelic administration. The epigenomic and transcriptomic changes induced by 2,5-Dimethoxy-4-iodoamphetamine (DOI), a subtype of psychedelics, in mouse neuronal nuclei at various time points suggest that the …
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The impact of stress on the prefrontal cortex: a view of how socioeconomic status impacts executive function
… to impact brain development especially the prefrontal cortex (PFC) which is a major region supporting executive function. Although the stress regulation mechanism seems valid, the influence of early life stress on the PFC and subsequent executive function outcomes have not been directly tested. …
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Moderate Ethanol Consumption by the Pregnant Guinea Pig Increases Ethanol Preference in Offspring
… forebrain structures, namely the hippocampus and frontal cortex. Pregnant Dunkin-Hartley-strain guinea pigs were given 24-h access to aqueous ethanol solution (5%, v/v) sweetened with sucralose (1g/L) or aqueous sucralose solution (1g/L) throughout gestation. Spontaneous locomotor activity in an …
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Near-Infrared Light Reduces Glia Activation and Modulates Neuroinflammation in Brain of Diet-Induced Obese Mice
… that in both hippocampus and parietal/occipital cortex, HFD caused increased expression of CD68 (activated microglia) and GFAP (astrocytic marker), whereas NIR light reverses this increase. On the other hand, the same investigations displayed no change in frontal cortex. Furthermore, I evaluated …
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