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Showing 1 to 20 of 76 for “"fiber diameter"”.
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Scaffold Permeability as a Means to Determine Fiber Diameter and Pore Size of Electrospun Fibrinogen
… the measurement of their topographical features (fiber and pore size) more accurate. Three different concentrations of fibrinogen were used (100, 120, and 150mg/ml) to create scaffolds with three different fiber diameters and pore sizes. The fiber diameters and pore sizes of the electrospun …
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Modeling and experimental analysis of electrospinning bending region physics in determining fiber diameter for hydrophilic polymer solvent systems
Electrospinning produces submicron fibers from a wide range of polymer/solvent systems that enable a variety of different applications. In electrospinning process, a straight polymer/solvent charged jet is initially formed, followed by a circular moving jet in the shape of a cone, called the …
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Investigation of a Simulated Annealing Cooling Schedule Used to Optimize the Estimation of the Fiber Diameter Distribution in a Peripheral Nerve Trunk
<p>In previous studies it was determined that the fiber diameter distribution in a peripheral nerve could be estimated by a simulation technique known as group delay. These results could be further improved using a combinatorial optimization algorithm called simulated annealing. This paper explores …
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Nerve Fiber Diameter Measurements Using Hematoxylin and Eosin Staining and Brightfield Microscopy to Assess the Novel Method of Characterizing Peripheral Nerve Fiber Distributions by Group Delay
… known to selectively impact various size nerve fibers, which often makes it difficult to diagnose which peripheral neuropathy a patient might have. The nerve conduction velocity diagnostic test provides clinically useful information in the diagnosis of some peripheral neuropathies. This method …
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Improved draw process in optical fiber fabrication
The performance of an optical fiber depends to a great extent on the conditions of the process being used to draw the fiber from a glass preform. To get fibers with higher strength and lower transmission loss, the parameters of the draw process must be optimized and the geometric uniformity of the …
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Tunability of Electrospun Scaffolds for Tissue Engineering
… tissue regeneration and growth with the proper fiber diameter for cell adhesion. However, electrospun scaffolds lack large pores between fibers and result in a densely packed mesh in which cells can adhere only to the surface of the material. Control of scaffold fiber size and porosity is …
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Complementary Strategies to Promote Mesenchymal Stem Cell Differentiation for Ligament Tissue Engineering
… poly(esterurethane urea) with variations in fiber diameter and fiber alignment. Primary mesenchymal stem cells and the mesenchymal stem cell line, C3H10T1/2, were seeded on these scaffolds and assumed spindle-shaped morphologies and oriented with the direction of fiber alignment. Fiber …
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Identifying and Reducing Variability, Improving Scaffold Morphology, and Investigating Alternative Materials for the Blood Vessel Mimic Lab Electrospinning Process
… increases with scaffolds of smaller fibers and pores than the current electrospinning protocol can produce. Finally, the Tissue Engineering Lab has interest in testing devices in more tortuous BVM bioreactor designs, however the use of relatively rigid PLGA scaffolds has severely …
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Bioresorbable Electrospun Tissue Scaffolds of Poly(ethylene glycol-b-lactide) Copolymers for Bone Tissue Engineering
… of electrospinning allows the fabrication of nanofiber scaffolds with topographical features the size of focal adhesion contacts capable of influencing cell behavior. Thus, the overall objective of this research project is to characterize electrospun PEG-PLA diblock copolymers as substrates for …
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The Influence of Branching and Intermolecular Interactions on the Formation of Electrospun Fibers
… that predict the onset of electrospun fiber formation and average fiber diameter. In particular, for neutral, non-associating polymer solutions, the minimum concentration required for fiber formation was the entanglement concentration (Ce), and uniform, bead-free fibers were formed at 2 …
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Preparation and Characterization of Electrospun Poly(D, L-Lactide-Co-Glycolide) Scaffolds for Vascular Tissue Engineering and the Advancement of an In Vitro Blood Brain Barrier Model
… inconsistent with one another with regards to fiber diameter (P < 0.0001), porosity (P < 0.0001), and wall thickness (P < 0.0001). However, the scaffolds were mechanically consistent (P-value of 0.6134) according to the calculated Young's modulii. The average fiber diameter for the electrospun …
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Near-Field Electrospinning and Characterization of Biodegradable Small Diameter Vascular Grafts
… ideal “off the shelf” tissue engineering, small-diameter (< 6 mm inner diameter (ID)) vascular graft hinges on designing a template that facilitates transmural ingrowth of capillaries to regenerate an endothelized neointimal surface. Previous traditionally electrospun (TES) approaches to create …
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DEVELOPMENT OF MAGNETIC FABRICS WITH TUNABLE HYDROPHOBICITY
Polystyrene (PS) fiber mats incorporating iron (Fe) particles were fabricated by electrospinning and the hydrophobicity of the resulting magnetic fabrics was investigated with and without an applied magnetic field. The results show that the hydrophobicity (as measured using water droplet contact …
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Development and Optimization of Imaging and Image Quantification Techniques for Tissue-Engineered Blood Vessel Mimics
… and implemented a MATLAB-based automatic fiber diameter measurement tool. Fiber measurements were obtained from a manual ImageJ method, a semi-automatic DiameterJ method, and a new automatic MATLAB method and compared to evaluate accuracy and user variability of the MATLAB tool. The …
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A Preliminary discourse on Adhesion of Nanofibers Derived from Electrospun Polymers
… (PVDF) were electrospun with an average fiber diameter of 333 ± 59 nm. Commercial cardboard with inorganic coating was used to provide a model substrate for adhesion tests. In SLBT, the elastic response PVDF was analyzed and its adhesion energy measured. FEA model with cohesive layer is …
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Electrospun Blends of Polydioxanone and Fibrinogen for Urological Applications
… to produce an engineered tissue scaffold. Fiber diameter and pore size of blends were characterized, as well as mechanical strength. Cell proliferation assays for 1 and 7 day cultures were preformed, and a histological evaluation was performed to determine how favorable the various blends …
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Model-free tracking control of an optical fiber drawing process using deep reinforcement learning
… approach for tracking control of an optical fiber drawing process is developed and evaluated. The DRL-based control is capable of regulating the fiber diameter to track either steady or varying reference trajectories in the presence of stochasticity and non-linear delayed dynamics of the …
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Genetic Analysis of Sheep Discrete Reproductive Traits Using Simulation and Field Data
… Heritabilities for grease fleece weight and fiber diameter were high for Targhee and Polypay sheep. Direct genetic correlations between growth and litter size were favorable for Suffolk and Targhee but weak for Polypay sheep. Genetic correlations between maternal effects for growth and direct …
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Design of an Electrospun Type II Collagen Scaffold for Articular Cartilage Tissue Engineering
… solution concentration (i.e. scaffold fiber diameter and pore properties) and as a function of the time in culture (evaluated at 2, 4, and 6 weeks). Fiber diameter had a linear relationship with concentration: mean diameter increased from 107 to 446 nm and from 289 to 618 nm, measured …
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