Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 18 of 18 for “"dwarfism"”.
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Some of the conditions which tend toward dwarfism and stunted physical development
… our subject is not restricted to cases of actual dwarfism, it seems better to adopt a broader basis of classification, such as: I. Cases of stunted physical development, due to the existence of some definite pathological change. II. Cases where no such pathological change is discoverable. As …
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Cytokinins tolerance and in vitro selection for dwarfism in apple (Malus x domestica Borkh.)
A reliable in vitro shoot regeneration system was developed for leaf segments of six apple (Malus Xdomestica Borkh) cultivars ('Wijcik', 'McIntosh', 'Macspur', 'Regal Gala' and 'M 26') grown in vitro using modified Murashige and Skoog (MS) medium supplemented with N-phenyl-N$\sp\prime$ …
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Vascular Disease Pathogenesis In Smooth Muscle Dysfunction Syndrome and Majewski Osteodysplastic Primordial Dwarfism Type Ii
… (SMDS) and Majewski Osteodysplastic Primordial Dwarfism Type II (MOPDII). SMDS is a rare condition due to pathogenic variants in <em>ACTA2 </em>p.Arg179, which lead to dysfunction of smooth muscle cells (SMCs) throughout the body. Complications of SMDS include early-onset thoracic aortic …
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Scope, Selectivity, and Mechanism of the Prins Cyclization of Delta,&egr;- and &egr;,zeta-Unsaturated Ketones With Lewis Acids to 1,3-Halohydrins
… however, overexpression of BAS1 gene induced dwarfism in transgenic creeping bentgrass by delaying vertical shoot growth and altering shoot architecture. True BAS1 transformants (BS1305, BS1307, BS1701) had the best performance in most traits even under reduced PPF and R:FR.
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Genetic improvement of selected indigenous Cucurbitaceae species important for food and medicinal purposes in KwaZulu-Natal, South Africa
… germinability (germination percentage), induced dwarfism, enhanced stem branching, reduced leaf area and number of stomata, and increased guard cell length and leaf chlorophyll content in both species. In C. palmata, colchicine treatment increased root fresh and dry weight but reduced shoot fresh …
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Arabidopsis thaliana P4-type ATPases ALA4 and ALA5 are Necessary for Normal Cellular Elongation in Developing Vegetative Tissues and Rescue the Pollen Tube Deficiencies in Knockout ala6/7 Mutants
… loss of function mutant for ala4/5 results in dwarfism for all vegetative tissues, including roots, leaves and hypocotyls. Selected cell types in these tissues were shown to be smaller. While a restoration of growth to near wild type levels was observed for dark grown ala4/5 hypocotyls in the …
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The role of the PWWP domain in the DNA methyltransferase 3A targeting to the genome
… Similar mutations in humans cause primordial dwarfism. I found that oocytes of Dnmt3a-D329A mice show no alterations in DNA methylation. However, the D329A mutation causes dominant postnatal growth retardation in mice. At the molecular level, it results in aberrant progressive acquisition of …
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Forward genetic analysis of cellulose biosynthesis inhibitor resistance and wall hydrolysis sensitivity.
… characterized by reduced crystallinity and dwarfism. These results provide genetic evidence supporting CESA1-CESA3, and CESA3-CESA6 association with flupoxam and isoxaben respectively targeting and disrupting these interactions. The ixr and fxr mutants also exhibited enhanced …
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MOLECULAR CHARACTERIZATION OF THE PUTATIVE NUCLEOTIDE- BINDING AND HYDROLYZING ACTIVITIES OF THE ELLIS VAN CREVELD (EVC) PROTEIN
… disorder that is characterized by short-limb dwarfism, extra fingers or toes, malformed teeth and nails, and congenital heart defects. Mutations in two genes, EVC and EVC2, which are located on chromosome 4, have been shown to be responsible for EvC syndrome. The protein products of these …
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Regulation of natriuretic peptide system activation:effects of spontaneous natriuretic peptide mutations and identification of novel natriuretic peptide receptor phosphorylation sites.
… point mutation in mouse CNP (CNPlbab) leads to a dwarfism phenotype caused by reduced binding to and activation of GC-B. A naturally occurring familial mutation correlated with early onset atrial fibrillation which alters the length of ANP (fsANP) does not alter ligand-receptor activation but …
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Ecological Assembly of Leaf-Litter Anuran Communities Across a Neotropical Land-Bridge Archipelago
… towards insular gigantism in small species, and dwarfism in large species – contrasting with previous findings on other vertebrates. In the second chapter, I provide support for a positive relationship between the strength of anti-predator coloration, agonistic behavior, and dominance in …
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PHOTOPERIODIC REGULATION OF RICE STEM ELONGATION BY THE GENE PINE1
… Some of the generated plants did show strong dwarfism, indicating that some mutation in the promoter region lead do a PINE1 overexpression. For the same purpose of finding ways to control plant height, we also identified some candidate genes controlled by PINE1 using RNA sequencing and created …
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A genetic analysis of reproduction in growth selected lines of chickens
… backgrounds. The depressive effect of the dwarfism was more severe in the LW than HW line and for body weight than for skeletal growth. In the B₃ and B₄ generations, the HW dwarfs matured 5 days earlier, while the LW dwarfs matured 6 days later than their normal sibs. On a percentage …
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Generation and characterization of spred-2 knockout mice
… to achondroplasia, the most common form of human dwarfism. Spred-2-/- mice showed reduced growth and body weight, they had a shorter tibia length and showed narrower growth plates as compared to wildtype mice. Spred-2 promoter activity and protein expression were detected in chondrocytes, …
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Transcriptional regulation of seasonal desiccation tolerance in the fronds and rhizome of the fern Anemia caffrorum
… to the DT phenotype, were genes that promote dwarfism and reduced photosynthetic potential in fronds. Altogether, the study has provided possible candidate genes that may govern the DT phenotype and has underscored the significant interplay between these organs in achieving seasonal tolerance.
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Little Bodies, Little People: Conflating the Child and the Dwarf in The History of Sir Thomas Thumb
<p>Despite Victorian and disability studies scholars’ recent interest in Charlotte M. Yonge, little scholarship focuses on her children’s fiction or the ways it engages with disability. This thesis brings a disability studies reading to Yonge’s under-studied novel, <em>The History of Sir Thomas …
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PCO2 EFFECTS ON THE PRODUCTION OF PELAGIC BIOGENIC CARBONATE AND OCEAN CHEMISTRY: A CASE HISTORY FROM THE CRETACEOUS.
… reduced size and marked ellipticity. Coccolith dwarfism and “deformation/malformation” are interpreted as the coccolithophorid species-specific response to surface-water acidification. Nannofossil abundance and paleofluxes recover after most extreme conditions are reached in the early phase of …
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Estudio molecular de pacientes colombianos afectados por enanismo esencial
Los síndromes de enanismo esencial microcefálico son un grupo de enfermedades monogénicas infrecuentes que se caracterizan principalmente por talla baja extrema proporcionada de inicio prenatal y microcefalia severa. En los pacientes que formaron parte del presente estudio se investigaron variantes …