Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 49 for “"denervation"”.
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Neonatal striatal dopamine denervation: consequences of P0 and P7 lesions
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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The Effects of Denervation and Arterial Ligation on Calcium Turnover in Bone
Contrary to earlier concepts, it is now recognized that bone takes an active and important part in the general homeostasis of the body. Bone in turn is profoundly affected by changes in the internal and external environment, leading to manifold pathologic conditions, the most common among them …
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Effect of Denervation on the Regulation of Mitochondrial Transcription Factor a Expression in Skeletal Muscle
… myofiber size and mitochondrial content during denervation, a muscle disuse model, occurs during the first week following the onset of the stimulus. In this study, we analyzed the expression of Tfam, a critical mitochondrial transcription factor involved in the orchestration of mitochondrial …
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MACROPHAGE RESPONSE TO INITIAL MUSCLE DENERVATION IN THE SOD1-G93A MOUSE MODEL OF AMYTROPHIC LATERAL SCLEROSIS.
… In the SOD1G93A mouse model of ALS, initial NMJ denervation occurs in the TA muscle (FF and FR fibers) between postnatal day (P)14 and P30, while little denervation occurs in soleus muscle (S and FR fibers) even late in disease. It is plausible that early alterations in the neuronal …
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Study of biological phenomena implicated in neuromuscular ageing
… oxygen species (ROS) are linked to pathological denervation in multiple neurodegenerative diseases, but whether and how ROS causes denervation is unclear. Our main hypothesis was that ROS recapitulates the signalling pathways of developmental denervation to cause pathological denervation in …
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Evaluation of patients with resistant arterial hypertension before and after pharmacological treatment correction or a renal artery sympathetic denervation procedure /
… patients who underwent sympathetic renal artery denervation procedure in 2012-2017. There was a statistically significant blood pressure (BP) reduction in after 6 months in groups. However, decrease in systolic BP was significantly higher in interventional group -33.8 mm Hg (± 3.01) vs. -26.6 mm …
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An Electrophoretic Analysis of the Denervation-Induced Changes in Soluble Protein Content of Regenerating Forelimbs of the Adult Newt, Notophthalmus Viridescens
Made available in DSpace on 2014-12-12T01:27:45Z (GMT). No. of bitstreams: 1 7500290.pdf: 1867112 bytes, checksum: fb8ee79b91fbeeb356e0bc31913a9732 (MD5) Previous issue date: 1974
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Renal failure and the neural control of the kidney
… almost completely corrected by bilateral renal denervation. The integrity of the low-pressure cardiopulmonary receptors to inhibit RSNA was investigated using acute saline volume. Again, a blunted reflex sympatho-inhibition of RSNA was observed, which was corrected by renal denervation. Finally …
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Die Arthroskopie bei Erkrankungen des Handgelenks
… mit konservativer Behandlung, Débridement und Denervationen erzielt werden. Hier betrug die Handgelenksbeweglichkeit postoperativ 91 % im Vergleich zur Gegenseite, die Kraft 73 %. 75 % der Patienten gaben eine Schmerzlinderung an. Die Patienten mit zweitgradiger skapholunärer Dissoziation (n=5) …
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Assessing The Therapeutic Viability of Hsc70 in ALS
… neurodegenerative disease, characterized by the denervation of the neuromuscular junction and death of motor neurons. When cells face stressful insult the heat shock response is activated in an attempt to reduce intracellular calamity. The heat shock response is identified by the increased …
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The Apoptotic and Wallerian Degeneration Pathways Regulate Disease Onset and Progression in the SOD-1G93A Transgenic Mouse Model of ALS
… disorder characterized by progressive muscle denervation, motor axon degeneration and the death of motor neurons. The molecular mechanisms that mediate axon degeneration in ALS remain unknown, but motor neuron cell body death occurs through apoptosis. Genetic deletion of the pro-apoptotic gene …
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Rezistentiška arterine hipertenzija sergančių pacientų įvertinimas koregavus medikamentinį gydymą bei po simpatinės inkstų arterijų denervacijos /
… patients who underwent sympathetic renal artery denervation procedure in 2012-2017. There was a statistically significant blood pressure (BP) reduction in after 6 months in groups. However, decrease in systolic BP was significantly higher in interventional group -33.8 mm Hg (± 3.01) vs. -26.6 mm …
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Pitx3Null Mutant (Striatal Dopamine-Deficient) Mice Have Exaggerated Spiny Projection Neuron Responses to l-DOPA and D1 Agonism and Lack Baseline Striatonigral Spiking
… mouse's Parkinson's-like gradient of striatal DA denervation. Evidently, chronic DA denervation renders SPNs hyper-responsive to l-DOPA and a D1 agonist, SKF 81297, as indicated by exaggerated SPN spike rate responses biased by low baselines in <em>Pitx3</em>Null mice compared to wild-type mice. …
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Interaction Of Afferent Renal Nerve Activity And Il-1R Signaling In Hypertension
Renal denervation was recently approved by the FDA for the treatment of hypertension, but the mechanism by which it reduces blood pressure is unclear. Studies of patients who have received the treatment have shown a variety of off-target improvements in conditions associated with sympathetic …
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Regulation of Skeletal Muscle Innervation and ALS Pathogenesis by MicroRNA 206
… is dramatically upregulated following surgical denervation of skeletal muscle and in a mouse model of amyotrophic lateral sclerosis (ALS). The responsiveness of the miR-206 gene to the state of motor innervation is dependent on binding sites for MyoD in an upstream enhancer. Based on the …
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