Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 141 for “"dca"”.
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Sodium dichloroacetate (DCA) impairs β-secretase-mediated proteolysis of the alzheimer's disease amyloid precursor protein (APP)
… the mitochondrial modulator dichloroacetate (DCA) impairs the β-secretase-mediated processing of APP as determined by impaired sAPPβ production. Conversely, the non-amyloidogenic processing of APP was enhanced resulting in more sAPPα production. Over-expressing the β-secretase (BACE1) in …
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Characterizing the chemistry of yellow-poplar surfaces exposed to different surface energy environments using DCA, DSC, and XPS
… have been described using dynamic contact angle (DCA) and X-ray photoelectron spectroscopy (XPS) analysis. Results show that the surface molecular orientation of yellow-poplar can be controlled by increasing the temperature above the Tg of lignin with exposure to either an environment of higher …
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Surface Catalyzed Fenton Treatment of bis(2-chlorethyl) ether (BCEE), bis(2-chloroethoxy) methane (BCEM) and 1,2-dichloroethane (1,2-DCA)
… methane (BCEM), and 1,2-dichloroethane (1,2-DCA) among other contaminants. Parameters that affect the contaminant loss rate such as pH, hydrogen peroxide concentration and solid/water ratio were systematically evaluated. Batch reactors were set-up utilizing either contaminated or …
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Investigating the Potential of Microbial Metabolites and mTOR Signaling on Chicken Necrotic Enteritis
… g/kg (on top of basal diet) deoxycholic acid (DCA). The birds were challenged with Eimeria maxima (20,000 oocysts/bird) at d 18 and C. perfringens (109CFU/bird/day) at d 23 and d 24 to induce NE. Birds were sacrificed at d 26, and ileal tissue and digesta samples were collected. DCA alleviated …
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Bioremediation of chlorinated ethanes and ethenes in vertical flow engineered wetland systems
… treatment wetland bed. 1,1-dichloroethane (1,1-DCA) and cis-1,2-dichloroethene (cis-1,2-DCE) were used as the chemicals of interest. The presence of cis-1,2-DCE inhibited dechlorination of 1,1-DCA but cis-1,2-DCE dechlorination was not affected by the presence of 1,1-DCA. Simulation runs showed …
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Enhanced Dechlorination of 1,2-Dichloroethane by Coupled Nano Iron-Dithionite Treatment
1,2-dichloroethane (1,2-DCA) is a chlorinated solvent classified as a probable human carcinogen. Due to its extensive industrial applications, widespread contamination and recalcitrance towards abiotic dechlorination, 1,2-DCA remains a challenging compound for the remediation community and one of …
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Analysis of Production Data from Horizontal Shale Wells Using Decline Curves
… methods, only the Decline Curve Analysis (DCA) technique has proved successful in forecasting production data rapidly and to a high degree of accuracy. Several DCA models including conventional Arps, PLE, and Duong have been utilized in this study to determine the most appropriate method …
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Determining the mechanism of dichloroacetate-regulated processing of the Alzheimer’s disease-related amyloid precursor protein
… recently shown that orphan drug dichloroacetate (DCA) can inhibit the detrimental amyloidogenic APP processing pathway whilst boosting the beneficial non-amyloidogenic processing pathway. However, the mechanism(s) by which DCA exerts these effects are, as yet, unknown and, therefore, the current …
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Dichloroacetate, a inhibitor of pyruvate dehydrogenase kinase-1, attenuates hypoxia-induced resistance to 5-fluorouracil in gastric cancer cells
… treatment with low-dose dichloroacetate (DCA), an inhibitor of the glycolytic pathway. The expression profile of hypoxia-inducible factor-1α (HIF-1α) and pyruvate dehydrogenase kinase-1 (PDK-1) were analyzed in tissues from 10 patients with gastric cancer who had different responses to …
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Novel Interventions to Improve Cerebral and Peripheral Vascular Function
… parameter of dynamic cerebral autoregulation (dCA) (0.028 normalised gain%/mmHg-1, 95%CI= -0.080, 0.137, P=0.59). This study suggested that an acute bout of rIPC does not influence cerebrovascular function in healthy young individuals and older subjects with increased risk for CVD. In a …
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Estrategias de Autoanálisis Ocupacional en personas con discapacidad intelectual, daño cerebral adquirido y estudiantes.
… con discapacidad intelectual y daño cerebral (DCA), así como explorar las experiencias y los beneficios percibidos por las personas con discapacidad intelectual, DCA y estudiantes universitarios tras su participación en el programa. Del mismo modo, el propósito de esta tesis fue analizar el …
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THE BIOTRANSFORMATION OF BILE ACIDS BY A COMMON MEMBER OF THE BISON GUT MICROBIOME
… conjugates of cholic (CA) and deoxycholic acid (DCA) revealed it was a so-called broad spectrum BSH with preference for glycine-conjugates and DCA. Single crystal X-ray diffraction experiments resulted in 2 and 1.6 Å resolution structures of apo- and covalent AAA-10 inhibitor bound forms. The …
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Aging tests for dielectric-coated aluminum to be used in the Sudbury Neutrino Observatory
… measurement of dielectric-coated aluminum (DCA) mirror—the reflective component in the the concentrators. DCA is a standard product used in lighting fixtures to enhance the total reflected light. We determined that our application would best be served with a dielectric coating that was 10% …
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Characterization of polyethylene terephthalate, cellulose acetate and their blends
… (CA) and their blend. Dynamic Contact Angle (DCA) measurements are performed to obtain the surface free energies of PET and CA so that they can be compared to that from IGC. Moreover, the DCA data are used to calculate their spreading coefficients and the adhesive bond behavior between PET and …
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Variables neuropsicológicas y de tratamiento que predicen la independencia funcional en personas con Daño Cerebral Adquirido
… (IF) en personas con Daño Cerebral Adquirido (DCA), e identificar qué variables neuropsicológicas, además de otras variables relevantes, predicen el grado de actividad y participación de las mismas. El DCA a menudo genera la aparición de déficits de tipo sensorial, físico, cognitivo, conductual …
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Chemical-sensitive genes in zebrafish (Danio rerio) early development - identification and characterisation of differential expression in embryos exposed to the model compound 3,4-dichloroaniline
… toxicity. The 3,4-dichloroaniline (3,4-DCA), which is used as a reference compound in the DarT, was selected as model chemical in this thesis. In a first step, differentially expressed genes in embryos exposed to 3,4-DCA were identified by microarray technology and RT-PCR techniques. Six …
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Enhancing real-time embedded systems development using artificial immune systems
… of RTES. The Dendritic Cell Algorithm (DCA), an algorithm derived from the observed operation of the innate immune system which has previously been applied to a number of anomaly-detection problems, is included in a simulated RTES to detect deadline overruns in a task scheduling system, …
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Sum Frequency Generation Spectroscopy of Imidazolium-based Ionic Liquids with Cyano-functionalized Anions at Gas-Liquid and Solid-Liquid Interfaces
… ILs, such as [BMIM][SCN], [BMIM][DCA], [BMIM][TCM], and [EMIM][TCB] at the gas-liquid interface. By structural variation of the anion while keeping the cation constant, emphasis on the molecular arrangement of the anion at the gas-liquid interface was reported. Vibrational modes …
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The mechanism of photo-induced Stevens rearrangement of sulfonium ylides, and exploration of the chemical properties of ylidions
… by sensitization with dicyanoanthracene (DCA) have been experimentally explored.
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Understory vegetation patterns in oak savannas of the Missouri Ozarks
… and limestone/dolomite substrate types. DCA axes correlated with landscape variables and fire frequency, but correlations were generally weak, suggesting that differences in site history may be important in governing species composition. There was no significant difference between flora …
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