Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"copper-64"”.
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Copper-64 radiopharmaceuticals for receptor-mediated tumor imaging and radiotherapy
… several somatostatin analogues labeled with copper-64 for imaging and targeted therapy of SSTr positive cancer. Among three new cross-bridged bifunctional chelators coupled to Y3-TATE, 64Cu-CB-TE2A-Y3-TATE had the most favorable tumor targeting properties. The introduction of ionizable linker …
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Chromatographic studies and analytical methods development for selected tetraazamacrocycles and their copper(II) complexes
… interest due to their potential application as copper-64 radioisotope-based imaging and therapeutic agents. The development of separation conditions is important in evaluating their purity as well as assessment of their physical properties including conditional formation constants, acid …
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Biodistribution Studies of 64Cu-DOTA-Cetuximab after Intraperitoneal and Intravenous Injection in a Malignant Ascites Mouse Model of Human Gastric Carcinoma
… conducted a comparative biodistribution study of 64Cu-DOTAcetuximab in subcutaneous (SQ) tumor and MA mouse models. A mouse xenograft model of bilateral SQ tumors that express epidermal growth factor receptor (EGFR) was established by SQ injections of NUGC-4 and MKN-45 gastric cancer cells into …
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Development of 64Cu/NOTA-terpyridine platinum conjugates as chemoradiotheranostic agents
… (NOTA) pour la complexation cuivre-64 (64Cu, T1/2 = 12,7 h; EC, [43.1%]; β+, 0,653 MeV [17,8%]; β−, 0,579 MeV [38,4%]). Via l'émission d'électrons Auger et de positrons, le 64Cu est une source prolifique et locale de LEE qui peut détruire sélectivement les domaines sensibles de l'ADN …
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Development of new radiopharmaceuticals targeting the Cholecystokinin 2 receptor
Il percorso di studi sperimentali del presente Ph.D è stato incentrato sullo sviluppo di radiofarmaci innovativi e sulla loro valutazione preclinica. Il progetto è stato inquadrato all’interno della “filiera del radiofarmaco” nata a Catania grazie alla collaborazione instaurata tra il Center for …