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Showing 1 to 20 of 33 for “"cinnamic acid"”.
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Birch reduction of cinnamic acid
… this thesis the Birch reduction of cinnamic acid is investigated.</p>
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NOVEL CINNAMIC ACID-BASED DEHYDROPOLYMERS FOR EMPHYSEMA: IN VITRO AND IN VIVO ASSESSMENT OF THEIR ACTIVITIES
… pharmacotherapy. This project hypothesized that cinnamic acid-based dehydropolymers (DHPs), originally discovered as novel anti-coagulants, protect against emphysema through their potent triple inhibitory actions against oxidative stress, inflammation and elastase, some of the pathogenic …
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Characterization of alpha-cyclodextrin inclusion complexes with trans-cinnamic acid in an acid-based beverage system
… antimicrobial to replace sodium benzoate, cinnamic acid was chosen. Due to cinnamic acid's solubility issues, α-cyclodextrin was used as a host molecule to form an inclusion complex with the cinnamic acid molecule. The cinnamic acid: α-cyclodextrin inclusion complex was then characterized …
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Effect of cinnamic acid-cyclodextrin inclusion complexes on populations of Escherichia coli O157:H7 and Salmonella enterica in fruit juices
Cinnamic acid (CA) is a naturally occurring organic acid that is found in some fruits and a number of spices. CA has antimicrobial activity against certain spoilage microorganisms and pathogenic bacteria. However, the acid is poorly soluble in water. Cyclodextrin molecules have a hydrophobic cavity …
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The Efficacy of Antimicrobials for the Control of Alicyclobacillus acidoterrestris in Fruit and Vegetable Juices
The efficacy of antimicrobials for control of A. acidoterrestris spoilage in juices was analyzed. Apple and tomato juices were inoculated with 4 log spores/ml. Antimicrobials were added at: 1000, 500 and 250 ppm (sodium benzoate, potassium sorbate, and sodium metabisulfite); 500, 250, and 125 ppm …
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Design, synthesis, and biological evaluation of Antimycobacterial agents from plant derived Betulinic acid, Oleanolic acid and their derivatives
… develop potent hit/drug leads for TB, betulinic acid (BA) and oleanolic acid (OA) were isolated respectively from Curtisia dentata and Syzigum aromaticum. The 3-O- acetyl analogue of BA and OA were synthesized. The cinnamic acid conjugates at C-28 position of the four (4) synthesized compounds …
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Formation, Characterization and Stability of Natural Antimicrobial-Cyclodextrin Complexes
… are alkyl esters of para-hydroxybenzoic acid. The test compounds were evaluated for aqueous solubility as well as their solubility in an acid-based beverage mixture. The compounds were found to be practically insoluble (< 100 mg/L), very slightly soluble (100 mg/L – 1,000 mg/L) or …
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Development of Liquid Chromatography Mass Spectrometry technique for evaluation and differentiation of plant derived isomers
Cinnamic acid containing molecules have been shown to possess unprecedented pharmacological activities against various physiological disorders. Most of the plants containing these compounds have been shown to exhibit multiple bioactivities, notably against various diseases which are currently …
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Synthesis and Characterization of Novel Polyester Scaffolds from Sugarcane Industry By-products for Use in Skin and Bone Tissue Engineering
… non-toxic, biodegradable polyesters of aconitic acid, cinnamic acid and glycerol from by-products of the sugarcane industry as scaffolds for skin and bone tissue engineering. Utilizing the by-products, molasses and sugarcane bagasse, not only add value to the cane industry, but also paves path …
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Concentration dependency, mode of action and characterization of compounds involved in alfalfa autotoxicity
… phenolic compounds assayed, coumarin and trans-cinnamic acid were highly inhibitory to alfalfa root growth and shoot growth. The mixtures of phenolics were generally more phytotoxic than their respective individual components except in the case of coumarin and trans-cinnamic acid. Scanning …
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Towards Sacrificial Anode-Free Alkyne Electrocarboxylation
… oxidants to produce value-added carboxylic acids (C-acids) necessitates the development of more sustainable manufacturing alternatives. Electrocarboxylation offers a promising pathway to valorize carbon dioxide (CO₂) as a cheap and renewable carbon feedstock. However, current alkyne …
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Steady State and Theoretical Investigations of Peptidylglycine α-Amidating Monooxygenase (PAM)
… a series of substituted 2- (phenylthio)acetic acid analogs, leaving a product containing a free thiol capable of coordinating to copper(I). A series of cinnamic acid derivatives have been investigated as turnover dependent inactivators of PAM. It was shown that the inactivating compounds …
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Investigação dos efeitos antibacteriano e citotóxico de cumarinas
… of phenylalanine, taking as initial precursors cinnamic acid and p - hydroxy cinnamic acid, from which coumarins and their derivatives are biosynthesized by different routes. The potency of antibiotics is threatened by bacterial resistance, increasing the need for new drugs and new classes of …
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Stereo-directing effect of molecularly imprinted polymers on cinnamic acids
… imprinted polymers (MIPs) in reactions involving cinnamic acid derivatives, specifically focusing on (2E)-3-(4-methoxyphenyl) prop-2-enoic acid (trans-4-methoxy cinnamic acid (t-4MCA)). To the best of our knowledge, no prior studies have reported the synthesis of MIPs using t-4MCA as a template, …
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Anti-oxidant Action and Anti-aging Activity of Phenylpropanoid Compounds
… anti-inflammatory activity and effect of caffeic acid on wound healing in skin-incised mice. Materials & methods: The cinnamic acid derivaties, C_(6)-C₃ compounds, of Penylpropanoids are used. To investigegate the effects of anti-oxidant activity in cell free system, we measured DPPH radical …
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Impurity-coformer cocrystals and/or complexes and their use in separations
… examined using three systems: benzamide/benzoic acid, cinnamamide/cinnamic acid, and amoxicillin trihydrate/4-hydroxyphenylglycine system. Using the two model systems (benzamide/benzoic acid and cinnamamide/cinnamic acid), we demonstrated the feasibility of reducing the amount of the impurity …
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A study of the toxicological properties of propolis samples from Europe and Saudi Arabia and of their biological activity against protozoa
… (6), Chrysin (7), Apigenin (8), Pinostrobin (9), Cinnamic acid (10), Coumaric acid cinnamyl ester (11a) and Coumaric acid benzylester (11b). Two compounds were isolated from Polish propolis namely 4', 7-Dimethoxykaempferol (12) and Naringenin 4', 7-dimethyl ether (13), and three compounds from a …
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Efficacy of high pressure processing in combination with chemical preservatives for the reduction of Escherichia coli O157:H7 and Salmonella in apple juice and orange juice
… 125 ppm, hydrogen peroxide at 150 and 300 ppm, cinnamic acid, potassium salt at 125 and 250 ppm, potassium sorbate [KS] at 500 and 1000 ppm and sodium benzoate [NaB] at 500 and 1000). For both E. coli O157:H7 and Salmonella, the most effective antimicrobial was DMDC having a 5.79 and 5.96 log10 …
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Studies on the biosynthesis of podophyllotoxin:synthesis of labelled yatein and matairesinol, two potential precursors of podophyllotoxin
… alcohol derivative and a substituted hydroxy Cinnamic acid, although no "coupling" enzyme has been isolated to date. Further biosynthetic modifications of the coupled compound could lead to matairesinol and/or yatein, which have been proposed as potential biological precursors of …
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