Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 46 for “"behavioral tests"”.
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Development of a chronically implanted microelectrode array for intraneural electrical stimulation for prosthetic sensory feedback
… evaluated using both neurophysiological and behavioral tests. Animal studies have demonstrated single channel implant functionality of up to 129 days. The relative merit of the designs is assessed, and future directions for implant design and behavioral testing are suggested.
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Contributions Of the Human Medial Prefrontal Cortex To Associative Recognition Memory: Evidence From Functional Neuroimaging
… increasing interest from researchers. Using behavioral and functional magnetic resonance imaging measures, over two studies, this thesis provides evidence of a mnemonic role of the medial PFC. In the first study, participants were scanned while judging the extent to which they agreed or …
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The Effects of Rhes on Opioid Analgesia
… control littermates (rhes+/+) were subjected to behavioral tests to determine if any differences existed in opioid analgesia, tolerance, withdrawal, reward, and locomotion. Rhes-/- mice showed an increased opioid mediated analgesia, along with an absence of tolerance and decrease in withdrawal …
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The KATP -Knockout Mouse: A Model of Susceptibility to Post-Concussion Syndrome
… a mTBI. The present study was designed to assess behavioral and molecular changes post-mTBI in an animal model of genetic susceptibility to poor neurological outcomes, the Kir6.2-knockout mouse. We conducted multiple behavioral tests and analyzed the cellular stress response through assessment of …
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Indagine etnofarmacologica su Casimiroa edulis Llave et Lex
… on the central nervous system, different behavioral tests were performed: spontaneous motor activity, anxyolitic, antidepressant, hypnotic-sedative, anticataleptic, anticonvulsant, antinociceptive and antinflammatory activities. The results revealed that the extract of seeds reduced …
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Factors affecting neurogenesis after application of human mesenchymal stem cells in ischemic rat model
… We performed immunohistochemical studies and behavioral tests in transient middle cerebral occlusion rat model. Intravenous application of ex vivo cultured human mesenchymal cells, earlier (passage 2) or later (passage 6), was performed in stroke rat model. Compared to rat received later …
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The Effect of Grapes in Mice with Alzheimer's Disease and Brain Injury
… a grape-enriched or a control diet for 8 weeks. Behavioral tests were administered 2 weeks after injury. CCI mice showed significant motor and memory deficits, with no effect of diet. The grape-enriched diet trended towards the reduction of lesion volume and motor deficits in craniotomy mice. …
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The Association between Obesity, Cognition, and Visual Function
… causes: genetic vs. environment, were behaviorally characterized in order to determine which model was best suited to study behavioral and cellular changes associated with obesity. Furthermore, a suitable model needed to be identified to carry on studies focusing on the relation between …
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Objective Measures of Tinnitus in Humans
… treatments is by subjective measures (e.g. behavioral tests, questionnaires). Subjective methods, while important for clinical assessment, do not offer a reliable way to distinguish peripherally vs. centrally driven dysfunction in individuals with tinnitus. The goal of this dissertation …
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The Effects of Dendro[60]Fullerene on Neurobehavioral Outcome and Cerebral Vascular Function After Traumatic Brain Injury
… + hemorrhagic hypotension model. Additionally, behavioral experiments were performed to determine if DF-1 improved cognitive performance. These experiments determined that DF-1 did not preserve vascular function, but it did result in improved performance in behavioral tests, as well as a …
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An Investigation of Anxiety- And Depression-Like Behavior after Head Trauma in Mice
… this weight-drop model is, or if it was the behavioral tests that needed to be altered in order to measure anxiety and depression-like behavior more accurately.</p> <h1> </h1>
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Impact of prophylactic intranasal oxytocin administration on symptoms of post-traumatic stress
… and shock treatments, rats underwent various behavioral tests: re-exposure to the shock chamber to assess fear, elevated O-maze to assess anxiety, and food reward trials in the open field enclosure to assess reward-seeking behavior. The oxytocin treatment decreased fear related symptoms upon …
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Early Life Circadian Rhythm Disruptions Alters Brain and Behavior in Adulthood
… on executive functioning (i.e., series of behavioral tests to assess anxiety level, spatial memory, and working memory), circadian rhythmicity, and neural complexity in key brain areas. Results suggest that early life circadian disruptions impair executive functioning, and neural complexity …
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The development of a novel composite score to characterize effect size of behavior and histopathology changes after a repetitive mild traumatic brain injury
… and intra lab consistency in the assessment of behavioral and pathologic outcomes. Indeed, it remains unclear which behavior assessments are most useful in evaluating the effects of preclinical TBI. To investigate the relative contribution of various behavior tests in the assessment of …
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Effect of sinusoidal extremely low-frequency electromagnetic stimulation on neurons and glia in a transient stroke model
… and possible immunomodulatory response, behavioral tests, neuronal survival, and glial reactivity were assessed in vivo and in vitro. Results showed that ELF-EMS improved neurological outcome, locomotion, habituation, and anxiety in ischemia /reperfusion models. ELF-EMS also increased …
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Development of a Mouse Model of NY99 West Nile Virus-Induced Neurological Changes
… certain brain regions correlated with changes in behavioral tests investigating depressive-like behavior, sensorimotor gating, and motor learning, though there was no correlation with memory function. These studies show that this mouse model of WNV infection causes long-term changes in the brain …
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A Potential Role For Sap97 In Psychiatric Disorders
… In Chapter 2, we studied the transcriptomic and behavioral consequences of a viable, brain-specific conditional knockout of Sap97 (SAP97-cKO). RNA sequencing (RNAseq) from hippocampi from control and SAP97-cKO male animals identified 67 differentially expressed transcripts, which were …
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New materials for teaching computational thinking in early childhood education
… higher on academic, cognitive, social, and behavioral tests than students in a traditional elementary school setting. The Montessori Method is characterized by mixed-age classrooms, child-driven learning, and a series of sensorial, physical materials. Developed nearly 100 years ago by Dr. …
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Behavioral alterations in rat offspring following maternal immune activation and CXC chemokine receptor antagonism
… on the behavior of rat offspring, with behavioral tests chosen to examine cognitive functions that are typically impaired in human schizophrenia patients. The viral mimetic polyinosinic-polycytidylic acid (polyI:C) (4.0 mg/kg, i.v.) was injected into pregnant Long-Evans (LE) dams on …
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Promoting generalization of coin value relations with young children via equivalence class formation
… Their research describes specific behavioral tests to determine the establishment of properties that define the relations of equivalence. An equivalence relation requires the demonstration of three conditional relations: reflexivity, symmetry, and transitivity. The equivalence …
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