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Showing 1 to 20 of 57 for “"bactericidal activity"”.
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The Bactericidal Activity of Human Polymorphonuclear Leukocytes Before and After the Ingestion of Glucose
<p>The bactericidal test has been used to determine whether the consumption of concentrated carbohydrate affects the ability of human leukocytes to destroy bacteria. Subjects were given a dose of 100 grams of glucose. Two hours later a blood sample was drawn and incubated with Staphylococcus …
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Physiological Factors Affecting the Bactericidal Activity of the Western Fence Lizard (Sceloporus occidentalis) for the Lyme Disease Spirochete, Borrelia burgdorferi
… was quantified. Adult lizards had higher bactericidal activity than first-year juveniles, suggesting that complement-mediated inactivation develops with maturity and/or exposure to spirochete antigens. Also, bactericidal activity was positively associated with lizard tick load and body …
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High throughput measurement of antibody and complement mediated immunity to meningococcal disease
… of protection for meningococcal disease is serum bactericidal activity. The importance of bactericidal activity was established by Goldschneider et al. (1969) who demonstrated an inverse relationship between disease incidence and bactericidal titres of ≥1:4. The importance of antibody and …
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DISINFECTION USING A NOVEL HETEROGENEOUS CATALYST
… minutes exposure at room temperature. Increased activity was seen against all of the organisms at 35oC (after 40 mins exposure time log reductions of >5.39, 4.09 and >5.59 were recorded). Bactericidal activity was significantly increased when PCat was combined with H2O2. At room temperature …
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The Potential Role of Cathelicidin Peptides for the Treatment of Lower Respiratory Tract Infections
… three main outcomes: 1) the antimicrobial activity of CATH-2 and BLES+CATH-2 against multi-drug resistant, clinically isolated bacteria; 2) the immunomodulatory potential of both CATH-2 and BLES+CATH-2 in vivo; and 3) the bactericidal activity of BLES+CATH-2 treatment in vivo, using two …
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The Interaction of Neisseria Gonorrhoeae with Human Monocytes
… that killing was the result of intracellular bactericidal activity. Disruption of the monocytes by sonication to release internalized bacteria did not alter the number of viable colony-forming units recovered indicating that significant numbers of internalized gonococci fail to survive. …
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Use of solution-state nuclear magnetic resonance spectroscopy to determine the structures of medicinally relevant peptides and proteins
… among bacteriocins in that it has hemolytic activity in addition to bactericidal activity. Nisin, the prototypical lantibiotic, was studied in the context of the immunity protein, NisI, which is believed to confer immunity against lysis to the producing organism. The final system was …
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Selection and Characterization of Strains of Staphylococcus aureus Displaying Unusual Resistance to Aminoglycosides
… the effects of procedural variations on the activity of aminoglycosides have revealed that a single procedural change can significantly alter results, particularly in tests with Staphylococcus aureus (116,123). Variations in such factors as inoculum and type of medium used may at times also …
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Bacteriophage Endolysins: Anti-Infectives and Lysidiagnostics for the Post-Antibiotic ERA
… for initial characterization of hydrolytic activity, and (4) modifications of existing methods to optimize<em> in vitro</em> bactericidal activity. For <em>P. thiaminolyticus</em>, we identified the first endolysin to be described for this organism (LysPt9) that could achieve >3-logs of …
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Host-Defense Function of Anuclear Polymorphonuclear Neutrophil in Lung Injury
… barrier, phagocytosis of bacteria, and bactericidal activity. Adoptive transfer of PMNcyto into Pseudomonas aeruginosa (PA) infected mice showed a markedly reduced inflammatory lung injury. Unlike PMN, the host defense function of PMNcyto waned over time, first observed by in vivo …
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Proline-rich acidic protein 1 in Life and Death
… to the surface of bacteria. It demonstrates bactericidal activity and may aid bacterial phagocytosis. In colorectal cancer (CRC), PRAP1 is a downstream target of p53 and plays a protective role against genotoxic stressors. Repression of PRAP1 significantly enhances the anti-tumor effect of …
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Molecular cloning, structural characterisation and functional study of peptides from amphibian skin secretion
… were tested. In addition, the antimicrobial activity and antibiofilm activity of AMPs were assessed and their haemolysis activity was also tested. Apart from these, the relationship between structure and function of AMPs was determined by means of CD experiments and secondary structure …
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Genetically engineered phage fibers and coatings for antibacterial applications
… for the unmodified M13-Ag fibers. Conferred bactericidal functionality is determined via live-dead staining and a modified disk-diffusion (Kirby-Bauer) measure of zone of inhibition (Zol) against Staphylococcus epidermidis and Escherichia coli bacterial strains. Live-dead staining and Zol …
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Bacterial profiles and ex vivo effects of Salmonella Heidelberg on leukocyte function in turkey purebred lines
… and the ex vivo effects of SH on phagocytic and bactericidal leukocyte function in turkeys from six pedigree lines (A-F). Data were analyzed using JMP Pro (SAS) and differences were determined using Student’s t-test following ANOVA with significance reported at P ≤ 0.05. Interaction effects of …
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Effects of phytogenics on intestinal pathogenic bacteria and microbiota of non-ruminants
… medicine were screened and their antibacterial activity was demonstrated against Campylobacter jejuni, Listeria monocytogenes, Escherichia coli and Salmonella enterica subsp. enterica serovar Enteritidis. Agrimonia pilosa Ledeb, Smilax glabra Roxb, Anemone chinensis Bunge, and Iris domestica …
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Antimicrobial activity of human seminal plasma and seminal plasma proteins
… are degraded were responsible for the major bactericidal activity of seminal plasma. The activity of these peptides was strictly zinc-dependent. We also found potent antifungal activity in seminal unleashed by the acid vaginal pH. The antifungal activity was mediated by …
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Somatolactogenic hormones and interferon-gamma as regulators of neutrophil activation
… declines with advancing age, the effector activity of PMN from young and aged rats in response to both GH and IFN-$\gamma$ was compared. PMN from young rats demonstrated a higher capacity for oxygen-dependent killing of E. coli than those from the aged rats. These results defined an …
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Investigating FDA-Approved Drugs for Treatment of Multidrug-Resistant Neisseria gonorrhoeae
… were found to exhibit promising anti-gonococcal activity. Interestingly, three extremely potent and narrow-spectrum novel candidates, itraconazole, isavuconazole, and ravuconazole, are azole antifungals, and their activities were further investigated in vitro. Of the three azoles, ravuconazole …
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Antibacterial activities of silver-nanoparticles-titania composite thin films fabricated by the molecular precursor method (MPM)
… Composite films were found to have superior bactericidal activity than either neat TiO2 or Ag-only films, both in the dark and under visible light. Furthermore, films showed enhanced antibacterial activity under visible light than in the dark. In summary, all films exhibited bactericidal …
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