Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"bEnd.3"”.
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Cyclooxygenase-2 is Associated with Cadmium-induced ICAM-1 Expression in Brain Endothelial Cell
… ICAM-1 expression via NF-kB activation in bEnd.3 cerebrovascular endothelial cells. And also, we observed Cd induces cyclooxygenase-2 (COX-2) expression, and thereby prostaglandin E2 (PGE₂) production in bEnd.3. Based on the previous report that PGE₂ is one of the key regulators in the …
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The Role of PKC-δ in Hypoxia-induced Cerebrovascular Endothelial cell death.
… of PKC-δ during hypoxia-induced cell death using bEnd.3 cell, a cerebrovascular endothelial cell line. The activity of PKC-δ increased remarkably after 1 hour of hypoxic injury, and the increase was maintained until 4 hours of hypoxia. To investigate the role of PKC-δ during hypoxia in terms of …
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U0126, MEK1/2 inhibitor, Induces Adhesion Molecules Expression in Human Blood Cells
… brain endothelial cells and fibroblast cells. In bEnd.3 cells and NIH3T3 cells, U0126 had no effect on ICAM-1 expression. These results indicate that expression of adhesion molecule was increased by MEK1/2 inhibotors, such as U0126, in human blood cells and the expression of adhesion molecules may …
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The world's greatest wagon works : a history of the Studebaker Brothers Manufacturing Company, 1856 to 1966
… Brothers Manufacturing Company of South Bend, Indiana. The study also evaluated the impact upon the ethnic development of South Bend from the years 1856 to 1966.The applicability of the Kuhnian paradigmatic process of culture change to the South Bend-Studebaker interaction sphere was …
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Regulation des GPRC5B Rezeptors durch Hyperglykämie und pro-inflammatorische Zytokine
… der immortalisierten murinen Endothelzelllinie bEnd.3, der humanen primären Endothelzellinie HUVEC und der immortalisierten murinen glatten Gefäßmuskulaturzelllinie MOVAS auf mRNA und auf Protein Level untersucht. In allen Zelllinien konnte eine signifikante Hochregulation der endogenen GPRC5B …
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Role of KATP channels in angiogenesis
… in the mouse brain endothelial cell line bEnd.3. In addition, VEGF and CNP induced comparable capillary tube-like formation by Human Umbilical Vein Endothelial cells (HUVECs) in low growth factor Matrigel. All these in vitro pro-angiogenic endothelial responses were effectively abrogated …
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The effect of cutaneous vasculature on skin pigmentation
… using transwell system 4 C. Preparation of the bEnd.3/HUVECs conditioned medium 4 D. Ultraviolet (UV) irradiation of endothelial cells 5 E. Endothelial tube formation assay model using GeltrexTM Matrix 5 F. Hypoxia treatments 5 G. Melanin content and tyrosinase activity 5 H. Western blot …
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The Development of a Drug Delivery System Using Brain Endothelial Non-Antibody Binding Domains as Transport Carriers
… mouse and human brain endothelial cell lines, bEnd.3, and hCMEC/D3. Additionally, the overall enrichment of hTFR specific aptamers was demonstrated following twelve rounds of selection and high throughput sequencing of selected pools, data that warrants further investigation.
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Effect of IBC isolated from Psoralea corylifolia on expression of adhesion molecule-1 in cerebrovascular endothelial cells
… IBC on ICAM expression and leukocyte adhesion in bEnd. 3 cells and explored the possible mechanisms therein involved. IBC significantly down-regulated LPS-induced ICAM-1 expression and leukocytes-endothelial adhesion. IBC suppressed LPS-induced sequential events for NF-kB activation, that is, …
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Effect of Prostaglandin E2 on the Expression of Adhesion Molecules in Mouse Cerebrovascular Endothelial Cells
… cultured mouse brain endothelial cells and bEnd.3 cells and therein involved signaling pathways. PGE2 induced ICAM-1 expression at the levels of protein and mRNA levels in the time and dose dependent manner and the effects was mediated by EP1/4. In order to delineate the intracellular …
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Numerical Study Of A High-speed Miniature Centrifugal Compressor
… each component was analyzed. Loss due to turning bend was found to be significant in each component, even up to 30%. Tip leakage loss of small scale turbomachines has more impact on the impeller performance than that of large scale ones. Use of 10% tip gap was found to reduce impeller efficiency …
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Role of Cerebral Vasculature and Effect of Circulating Exosomes in Propagation of Systemic Inflammatory Responses into the Central Nervous System
… and cerebral microvascular endothelial cells (Bend.3). To further study their effects in vivo, SDEL were then intravenously injected into normal adult mice. The recipient mice that received SDEL exhibited elevated microglial activation. Moreover, increased astrogliosis, and elevated CNS …
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Effects of Cadmium on VCAM-1 Expression
… 중추신경계가 영향을 받는다고 알려져 있다. 본 연구에서는 마우스의 뇌혈관 내피세포인 bEnd.3에서 카드뮴을 처리했을 때 그로 인해 변화되는 부착분자 (adhesion molecule)의 발현이 어떠한 신호전달로 매개되는지를 알아보기 위하여, 카드뮴을 처리한 후 Vascular cell adhesion molecule-1 (VCAM-1)의 변화와 Mitogen Activated Protein Kinase (MAPK) 저해제들이 VCAM-1의 변화에 미치는 효과를 관찰하였다. 그 결과, 카드뮴 처리 2시간째 VCAM-1 …
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Adult Neural Stem Cells and Their Perivascular Niche
… potent than those secreted from the immortalized bend.3 endothelial cell line. Proliferation of activated stem cell astrocytes and transit amplifying cells with conditioned medium from primary cortical cells was shown to depend on EGFR in vitro. Here we define for the first time the effect of …