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Showing 1 to 20 of 161 for “"adhesion molecules"”.
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Liver Cell Adhesion Molecules in Embryonic Development
<p>Cell-cell adhesion is one of the essential processes for normal embryogenesis. The isolation and characterization of the neural cell adhesion molecule, N-CAM, provided the first substantial opportunity to study this process at a molecular level. Moreover, studies of N-CAM expression in embryos …
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Differential Expression of Cell Adhesion Molecules by Neuronal Injury
Cell adhesion molecules(CAMs) are expressed in glial cells and neurons play critical roles in development and maintenance of nervous system. CAMs are reported that may be key molecular determinants in the response of the nervous system to injury. Therefore we are thought to that the expression of …
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Homophilic and Heterophilic Interactions Among Cadherin Cell Adhesion Molecules
All three of the cadherins investigated in this thesis formed strong heterophilic bonds at three ectodomain alignments. Of the three, the inner bond (strongest) corresponding to full ectodomain overlap, did not exhibit much variation in either the homophilic or the heterophilic interactions. The …
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Biocompatible circuits : inflammation and soluble adhesion molecules after cardiopulmonary bypass
… cardiac surgical procedures. Soluble adhesion molecule (SAM) activation was studied at different time points and common clinical outcomes such as white blood cell activation, serum renal function parameters urea and creatinine, postoperative bleeding, transfusion requirements, …
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Plasticity in mice nociceptive spinal circuits -role of cell adhesion molecules.
… in the mouse and rat. On this basis, the role of adhesion molecules, in particular L1 adhesion molecules, in the nociceptive system is analyzed for the first time by using mutated mice. Results: It is confirmed that sensorimotor transformations performed by the NWR circuits abide the same …
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Expression of leukocyte-endothelial adhesion molecules during acute inflammation in the lung
Neutrophil (PMN)-endothelial cell adhesion is a critical step in the response of PMNsto inflammation. In the systemic circulation, the leukocyte adhesion molecule, L-selectin, facilitates PMN adhesion to inflamed endothelium while CD11/CD18 is required for PMN emigration into extravascular tissues. …
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Functional Significance of the Upregulation of Adhesion Molecules on Irradiated Endothelial Cells
… of the inflammatory response is leukocytes adhesion to the endothelium in a multi-step process involving leukocyte tethering to the endothelium, followed by rolling, firm adhesion/spreading and extravasation. Adhesion molecules mediate this process, particularly, E-selectin and ICAM-1, which …
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U0126, MEK1/2 inhibitor, Induces Adhesion Molecules Expression in Human Blood Cells
B₂-Integrin (CD11b) and L-selectin (CD62L) adhesion molecule play crucial roles in monocyte transmigration and adherence to endothelial cells, causing inflammatory responses in vascular lesion. MAPKinase pathway has been known to be activated in inflammatory responses. In this study, we …
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Effect of Prostaglandin E2 on the Expression of Adhesion Molecules in Mouse Cerebrovascular Endothelial Cells
Prostaglandin E2 (PGE2) is known to be the principal pro-inflammatory prostanoid and play an important role in brain disease through binding to four G protein-coupled receptor (EP1-4). However, there have been contradictory reports on its actions in inflammation processes. For instance, PGE2 …
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Interaction between cell adhesion molecules and stress hormones following different intensities of cycling exercise in obese males.
… (NE), and cortisol (COR)] and soluble cell adhesion molecules [soluble intercellular adhesion molecule 1(sICAM-1), soluble vascular cell adhesion molecule 1(sVCAM-1), and soluble endothelial selectin (sE-selectin)] over 24 hours following different intensities of exercise in obese men. In a …
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A Phenotypic And Genetic Characterization Of The Cell Adhesion Molecules Echinoid And Friend-Of-Echinoid In The Directed Cell Movements Of Ommatidial Rotation During Drosophila Eye Development.
… to functional tissues and organs. Differential adhesion between the stationary and mobile cells permits and promotes these cellular movements, effecting patterning of cells and tissues. During <italic>Drosophila</italic> eye development, groups of cells, the ommatidial precursors, undergo a …
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Molecular Basis of Cell Adhesion Mechanics
… maintenance of compact tissue structures. Cell adhesion depends on specialized adhesion molecules on the cell surfaces. Recent developments studying physical and chemical properties of the adhesion molecules have provided useful information in understanding the biological functions of the …
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Stochastic dynamics of adhesion clusters under force
Adhesion of biological cells to their environment is mediated by two-dimensional clusters of specific adhesion molecules which are assembled in the plasma membrane of the cells. Due to the activity of the cells or external influences, these adhesion sites are usually subject to physical forces. In …
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Role of ICAM-1, a cell adhesion molecule, in morphological changes of BV2 microglial cell
… the microglial cells. There are a series of cell adhesion molecules (CAM) related with these changes. In our present study, we studied the role of adhesion molecules including Intracellular adhesion molecule-1 (ICAM-1), which are responsible for the microglial activation using immortalized BV2 …
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Effects of IL-33 on the interaction between HMC-1 cells and human airway smooth muscle cells
… cells and HASM cells in vitro, analysing the adhesion molecules involved and the potential presence of chemokines relevant to the adhesion process. In addition, the effects of IL-33 on the above processes were also investigated. HMC-1 cells were analysed for the presence of several adhesion …
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Biophysical and Structural Studies of CNTNAP2
At synapses, cell adhesion molecules provide connection between the presynaptic and postsynaptic membranes through homophilic and heterophilic interactions promoting synapse development, function, and plasticity. The synaptic adhesion molecules contactin 2 (CNTN2), and contactin associated …
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Determining The Roles of Dendritic Cells and Icam-1 In The Transpresentation of Il-15 to Cd8 T Cells
… where antigen or IL-15 is limited, adhesion molecules are important for generating maximal responses. In vitro cultures between CD8 T cells and bone marrowdifferentiated DCs (BMDC) activated with a TLR agonist established a model of proliferation and signaling in CD8 T cells that was …
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Determining The Roles of Dendritic Cells and Icam-1 In The Transpresentation of Il-15 to Cd8 T Cells
… where antigen or IL-15 is limited, adhesion molecules are important for generating maximal responses. In vitro cultures between CD8 T cells and bone marrowdifferentiated DCs (BMDC) activated with a TLR agonist established a model of proliferation and signaling in CD8 T cells that was …
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